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Hypertension Clinical Trials

126 recruiting trials for Hypertension. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
126
Total Trials
126
Recruiting Now
6
Phase 3 Trials
10
Sponsors

Recruiting Trials

RECRUITINGNCT06001073

Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics

The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear....

Sponsor: First Affiliated Hospital Xi'an Jiaotong UniversityEnrolling: 250001 location
RECRUITINGNCT06153147

KIdney aNd blooD prESsure ouTcomes in Childhood Cancer Survivors (CCS)

Background: Childhood cancer survivors (CCS) are at elevated risk of chronic health conditions. Chemotherapies can cause recurrent acute kidney injury which may progress to kidney...

Sponsor: The Hospital for Sick ChildrenEnrolling: 5001 location
RECRUITINGNCT07180368

Assessment and Management of Multiple Drug Use in Elderly Chronic Disease Patients

The purpose of this observational study is to understand the impact of polypharmacy on the prognosis of elderly patients with chronic diseases. The main research question it aims...

Sponsor: Xijing HospitalEnrolling: 20001 location
RECRUITINGNCT06775028

Integrated Approach in Frail Older People with Atrial Fibrillation

The study will verify if a structured multidisciplinary approach (called iABC), aimed to improve the appropriate management of elderly AF patients with multimorbidity (the i-ABC...

Sponsor: Heart Care FoundationEnrolling: 125020 locations
RECRUITINGNCT07482462

Autonomic Regulation of Blood Pressure and Heart Rate During Orthostasis and Exercise in Healthy and Hypertensive...

The goal of this observational study is to assess arterial stiffness and autonomic regulation of blood pressure and heart rate in healthy adults and people with arterial...

Sponsor: University Medical Centre LjubljanaEnrolling: 1201 location
RECRUITINGNCT07425496

To Study Ocular Outflow Dynamics of the Eye Using Intraoperative Tonographic Biometry and Assess Its Predictive Value...

The objective of this study is to evaluate ocular outflow dynamics of the eye using intraoperative tonographic biometry and assess its predictive value in improving postoperative...

Sponsor: The New York Eye & Ear InfirmaryEnrolling: 1501 location
RECRUITINGPhase 2NCT06570473

Feasibility Trial for a Right Ventricular Failure Platform Trial

The primary objective of the CRAVE feasibility trial is to assess the feasibility of conducting a larger CRAVE platform trial by performing a randomized trial of 30 participants...

Sponsor: University of AlbertaEnrolling: 305 locations
RECRUITINGNCT05632601

Reexamining Her Cardiovascular Risk - Ottawa WomeN's Longitudinal Cohort Study

The full HER CROWN will be a prospective cohort study to propose a novel, women-specific cardiovascular risk score/ algorithm in the prediction of hard cardiovascular outcomes...

Sponsor: Ottawa Heart Institute Research CorporationEnrolling: 2101 location
RECRUITINGNCT05638269

A Multicentre Study on Features of the Gut Microbiota of Patients With Critical Chronic Diseases in China

The human gut microbiome has been associated with many health factors but variability between studies limits the exploration of effects between them. This study aims to...

Sponsor: Zhujiang HospitalEnrolling: 1200020 locations
RECRUITINGNCT06115122

PEPPI Study: Identification of Women at Risk for Placental Dysfunction

The main purpose of this study is to evaluate Fetal Medicine Foundation's pre-eclampsia risk calculator using maternal characteristics, first trimester serum placental growth...

Sponsor: Oulu University HospitalEnrolling: 30001 location
RECRUITINGPhase 4NCT07361679

LDA and LMWH vs LDA Alone in High-risk Patients for Preeclampsia Prevention

Preeclampsia is a major cause of maternal and perinatal morbidity and mortality worldwide. Low-dose aspirin started in the first trimester reduces the risk of preeclampsia in...

Sponsor: Alexandra Hospital, Athens, GreeceEnrolling: 1001 location
RECRUITINGNCT07261956

Lung Ultrasound for the Detection of Volume Overload in Patients With Severe Preeclampsia

This research aims to evaluate the usefulness of lung ultrasound (LUS) for detecting and monitoring fluid overload in patients with severe preeclampsia. Severe preeclampsia is a...

Sponsor: Saint Thomas Hospital, PanamaEnrolling: 2021 location
RECRUITINGPhase 3NCT07218029

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

Researchers are looking for more ways to treat PAH. In PAH, the blood vessels in the lungs become thick and narrow, which makes it harder for blood to flow. This causes high blood...

Sponsor: Merck Sharp & Dohme LLCEnrolling: 81520 locations
RECRUITINGPhase 3NCT06408181

APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia

The goal of this clinical trial is to investigate the effects of early initiation of double low-dose aspirin in pregnant women. The main questions it aims to answer are: Does...

Sponsor: University of PennsylvaniaEnrolling: 11501 location
RECRUITINGNCT07297342

A Prospective Randomnised Controlled Trial Comparing Overall Patient Compliance in a Bariatric Surgical Pathway Using...

The aim of this study is to assess the impact of a newly intensified digital platform following bariatric surgery. This will be measured using several questionnaires. The...

Sponsor: Sint Dimpna Ziekenhuis GeelEnrolling: 2001 location
RECRUITINGPhase 4NCT07140484

Sotatercept in Pulmonary Arterial Hypertension

The goal of this clinical trial is to determine whether sotatercept is effective in improving diffusing capacity in patients with pulmonary arterial hypertension. Participants...

Sponsor: University of AlbertaEnrolling: 271 location
RECRUITINGNCT04654650

Prospective Registry and Biobank for Long-term Observational Studies in Adult Patients with Pulmonary Hypertension

Prospective registry and biobank for long-term observational studies in adult patients with pulmonary hypertension

Sponsor: Universitätsklinikum Hamburg-EppendorfEnrolling: 50001 location
RECRUITINGNCT06852924

Inhaled Nitric Oxide for High Amplitude Pulmonary Edema (HAPE)

High Altitude Pulmonary Edema (HAPE) is a critical, non-cardiogenic pulmonary edema that manifests in high-altitude conditions, marked by the rapid onset of symptoms such as...

Sponsor: Novlead Inc.Enrolling: 1001 location
RECRUITINGNCT06432582

hepatomiR cACLD Study

This study looks to gather data on hepatomiR, a CE-certified test already intended for gauging liver-related outcomes, in order to define a cut-off regarding specific...

Sponsor: Karl Landsteiner University of Health SciencesEnrolling: 1561 location
RECRUITINGPhase 1 / Phase 2NCT06826859

Daily Aspirin vs Split Dosing in High-risk Pregnancies (DASH)

Aspirin is recommended in high risk patients to reduce the risk of preeclampsia and preterm birth, which are leading causes of both maternal and neonatal morbidity and mortality,...

Sponsor: Thomas Jefferson UniversityEnrolling: 4001 location
RECRUITINGNCT06280313

Impact of Splenectomy on the Efficacy of Targeted Therapy and Immunotherapy in Unresectable HCC Patients With Cirrhotic...

Currently, the combination of targeted therapy and immunotherapy is the first-line treatment for advanced hepatocellular carcinoma (HCC). However, a subset of HCC patients with...

Sponsor: Zhiyong HuangEnrolling: 601 location
RECRUITINGNCT07229196

Clinical Trial in Hypertensive Patients Comparing Two Cardiorespiratory Exercise Protocols, Low-volume Sprint Interval...

This randomized clinical trial aims to compare two cardiorespiratory exercise training protocols - Sprint Interval Training (SIT), characterized by short, maximal-intensity...

Sponsor: Unidad Enfermedades Cardiometabolicas- Hospital Interzonal General Agudos San Martin de La PlataEnrolling: 201 location
RECRUITINGNCT06876896

Intra-abdominal Pressure (IAP) During PFA Treatment of A-fib/ A-Flutter

The purpose of this study is to investigate the intra-abdominal pressure utilizing the Accuryn monitoring system during pulsed field ablation procedures in the electrophysiology...

Sponsor: Wake Forest University Health SciencesEnrolling: 501 location
RECRUITINGPhase 2NCT07297797

Phase II Clinical Study of HRS-9563 in Patients With Mild to Moderate Hypertension

This study aims to evaluate the efficacy and safety of HRS-9563 in patients with mild to moderate hypertension, and to explore its appropriate dosage.

Sponsor: Fujian Shengdi Pharmaceutical Co., Ltd.Enrolling: 2341 location
RECRUITINGEarly Phase 1NCT06168461

Daily Aspirin Treatment After Preeclampsia

Women who develop preeclampsia during pregnancy are four times more likely to develop cardiovascular disease later in life, even if they are otherwise healthy. The reason why this...

Sponsor: Anna Stanhewicz, PhDEnrolling: 401 location
RECRUITINGNCT07423741

Ultrasonographical Assessment of Airway Indices in Pregnancy

Clinical and ultrasound indices of airway, in addition to laryngoscopic view will be assessed and compared among three groups of patients: non pregnant, pregnant with normal blood...

Sponsor: South Valley UniversityEnrolling: 1801 location
RECRUITINGNCT05027685

The "Global Paradise System" Registry

The GPS Registry is a multi-centre, single-arm, non-interventional (observational) registry. In addition to collecting data from patients treated as per standard clinical...

Sponsor: ReCor Medical, Inc.Enrolling: 300020 locations
RECRUITINGNCT06966713

Predict Severe Traumatic Brain Injury

Severe traumatic brain injury (TBI) is associated with a 20-30% mortality rate and significant disability among most survivors. The Centers for Disease Control and Prevention...

Sponsor: University of ChicagoEnrolling: 1202 locations
RECRUITINGPhase 1NCT07036510

Safety of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract...

The goal of this clinical trial is to test a new method to deliver an approved medicine called Timolol in the eye of participants with glaucoma or ocular hypertension and...

Sponsor: EyeD PharmaEnrolling: 181 location
RECRUITINGNCT03799653

A Nurse Cohort Study in Xiamen, China

The Nurse Cohort Study Xiamen (NCSX) is an open-ended prospective cohort study with very broad research aims. The primary objectives of the NCSX is planned to examine genetic,...

Sponsor: The First Affiliated Hospital of Xiamen UniversityEnrolling: 100001 location
RECRUITINGPhase 1NCT06773975

The Effect of an Oral Nutritional Supplement on the Nutritional and Health Outcomes of the Elderly

I am conducting this research to find out if a peanut based food that is ready to use would improve the nutritional and health outcomes of the elderly when they consume it daily...

Sponsor: University of GhanaEnrolling: 801 location
RECRUITINGNCT06192251

Complete Lifestyle Medicine Intervention Program

This project will use a mixed design and will be conducted at the West Parry Sound Health Centre. Based on similar studies there is an expected 10% drop-out rate so 20...

Sponsor: Northern Ontario School of MedicineEnrolling: 81 location
RECRUITINGNCT06647511

Digital Solutions to Reduce Maternal Morbidity and Mortality in Pregnant Refugee Women

The goal of this observational study is to use digital health tracking to improve how high blood pressure and other health issues are detected in pregnant refugee women. The main...

Sponsor: Weill Medical College of Cornell UniversityEnrolling: 751 location
RECRUITINGNCT06612099

Comparison of the Effects of Aerobic Exercise Training and Mat Pilates Exercise on Blood Pressure, Functional Capacity...

The research aims to compare two different exercise approaches applied to hypertensive individuals. After completion of the research, it will be revealed which exercise approach...

Sponsor: Bezmialem Vakif UniversityEnrolling: 271 location
RECRUITINGNCT00710177

PTGS1 Genetic Variation and Increased Risk for Persistent Pulmonary Hypertension of the Newborn

The purpose of this study is to determine if normally occurring variations in a specific gene called PTGS-1 are associated with an increased risk of narrowing of the ductus...

Sponsor: Medical College of WisconsinEnrolling: 2001 location
RECRUITINGPhase 4NCT07288801

Vitamin D for Preventing Recurrent Preeclampsia in Pregnant Women

The goal of this clinical trial is to find out whether giving vitamin D to pregnant women who had pre-eclampsia in a previous pregnancy helps prevent the condition from coming...

Sponsor: Nishtar Medical UniversityEnrolling: 1461 location
RECRUITINGNCT07265336

Excess Base Comparison Between Pregnant Subjects With Severe Preeclampsia vs. Normotensive Pregnant Women

The study's primary goal is to compare the base excess (BE) values-an indicator of metabolic changes-in two groups of patients at Santo Tomás Hospital: those with severe...

Sponsor: Saint Thomas Hospital, PanamaEnrolling: 1001 location
RECRUITINGPhase 4NCT06132477

Impact GLP-1 Agonists Following Bariatric

Glucagon-like peptide 1 (GLP-1) is a hormone that helps regulate blood glucose levels through improved insulin sensitivity and release of insulin from the pancreas, control...

Sponsor: University of Missouri-ColumbiaEnrolling: 1501 location
RECRUITINGNCT03312556

Treatment of Supine Hypertension in Autonomic Failure (CPAP)

Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of...

Sponsor: Vanderbilt University Medical CenterEnrolling: 121 location
RECRUITINGPhase 4NCT06523465

Statin Combined with Amlodipine Treats Primary Aldosteronism

The drug treatment for primary aldosteronism (PA) is limited and difficult to improve long-term cardiovascular outcomes. This study plans to enroll patients with primary...

Sponsor: Third Military Medical UniversityEnrolling: 1801 location
RECRUITINGNCT05968859

A Study of Pulmonary Hypertension Peripheral Limitations

The investigators are doing this research study to compare whole body aerobic training with isolated leg training (with weights) and its impact on effectiveness in symptoms and...

Sponsor: Mayo ClinicEnrolling: 451 location
RECRUITINGNCT06647888

Evaluation of Enavogliflozin's Efficacy and Safety in Type II Diabetes With Hypertension or Dyslipidemia

This observational study is a non-interventional, multi-center, prospective observational study aimed at tracking the efficacy and safety of Envlo or Envlomet SR tablets for 24...

Sponsor: Daewoong Pharmaceutical Co. LTD.Enrolling: 120001 location
RECRUITINGNCT06643741

Non-Invasive Preeclampsia Screening and Biobank

Women pregnant between 11-14 weeks gestation will be enrolled with blood samples collected to evaluate for preeclampsia.

Sponsor: Sequenom, Inc.Enrolling: 655020 locations
RECRUITINGPhase 3NCT06174766

A Study to Evaluate Efficacy and Safety of HGP2102 in Essential Hypertension Patients

A Multicenter, Randomized, Double-blind, Phase 3 Study to Evaluate the Efficacy and Safety of HGP2102 in patients with Essential Hypertension

Sponsor: Hanmi Pharmaceutical Company LimitedEnrolling: 3241 location
RECRUITINGNCT01884051

Hormonal, Metabolic, and Signaling Interactions in PAH

Our hypothesis is that optimal treatment of the dysfunctional metabolic pathways which underlie PAH will improve pulmonary vascular function and consequences of the disease.

Sponsor: Vanderbilt University Medical CenterEnrolling: 18991 location
RECRUITINGNCT07019246

Safety of Etomidate-propofol Mixture vs. Propofol for Total Intravenous Anesthesia in Elderly Patients Undergoing...

The purpose of this study is to access the safety of etomidate - propofol mixture vs propofol for total intravenous anesthesia in elderly patients undergoing abdominal surgery.

Sponsor: Tongji HospitalEnrolling: 1661 location
RECRUITINGNCT05411029

Study of Disrupted Sleep in Somali Americans

The aims of this study are to determine the types and severity of previously undiagnosed sleep deficiencies in otherwise healthy Somali Americans, apply a research framework to...

Sponsor: Mayo ClinicEnrolling: 2401 location
RECRUITINGPhase 1NCT06258473

Addressing Gaps in the Hypertension and Diabetes Care Continuum in Rural Bangladesh: The Dinajpur Study

In the present implementation study, we aim to document the experience of implementing integrated, decentralized primary care in rural Bangladesh, including components of...

Sponsor: BRAC UniversityEnrolling: 67501 location
RECRUITINGNCT07291141

A Comparative Study of MRI and Ultrasound for Detection of Primary Hepatocellular Carcinoma, Body Composition and Risk...

DETECT-HCC-ESLD is a prospective multicenter study designed to examine early detection and risk stratification of hepatocellular carcinoma (HCC) in individuals with advanced liver...

Sponsor: Mattias EkstedtEnrolling: 6001 location
RECRUITINGNCT06057051

Glaukos® iStent Infinite Trabecular Micro-Bypass System in Subjects With Mild to Moderate Primary Open-angle Glaucoma

Prospective, multicenter, single-arm study of the iStent infinite in adult pseudophakic or phakic subjects with mild to moderate primary open angle glaucoma who have not failed...

Sponsor: Glaukos CorporationEnrolling: 2451 location

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