A Multicentre Study on Features of the Gut Microbiota of Patients With Critical Chronic Diseases in China

Who May Qualify: 1. aged 18-75 years; 2. living in the province where the hospital is located in the last three years; 3. with a medical diagnosis of one of the target diseases; 4. willing to provide written willing to sign a consent form. Who Should NOT Join This Trial: 1. female in pregnancy or lactation(unless the subject is pregnant women); 2. with medical diagnoses of other serious illnesses; 3. with a history of bariatric surgery or intestinal resection, except for appendectomy； 4. individual who was treated with drugs in the preceding 1 month, including antibiotics, metformin, statins, acid inhibitor, probiotics, and probiotics; individuals having consumed yogurt more than 3 times in the preceding 1 month; heavy drinkers who have consumed more than 4 taels of liquor or 1000ml of beer; frequent alcohol consumers who have drunk per week in the last month. Always talk to your doctor about whether this trial is right for you.