RECRUITINGOBSERVATIONAL

hepatomiR cACLD Study

Assessment of a hepatomiR Cut-off for Predicting Specific Hepatic Decompensation Events in Advanced Chronic Liver Disease

About This Trial

This study looks to gather data on hepatomiR, a CE-certified test already intended for gauging liver-related outcomes, in order to define a cut-off regarding specific decompensation events (ascites, variceal hemorrhage, hepatic encephalopathy) in chronic liver disease (CLD). Based on these data, it is aimed to advance the current understanding of factors driving decompensation, with potential repercussions for future risk management and therapy.

Who May Be Eligible (Plain English)

Who May Qualify: - Age ≥ 18 years - Chronic liver disease (more than 6 months) - LSM ≥ 10 kPa - Outpatient at the Clinical Department of Internal Medicine II, University Hospital St. Pölten - Signed patient consent form Who Should NOT Join This Trial: - Age older than 18 years - Pregnancy - Primary hepatic malignancy (hepatocellular carcinoma, cholangiocarcinoma) with portal invasion and/or extrahepatic spread Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Inclusion Criteria: * Age ≥ 18 years * Chronic liver disease (more than 6 months) * LSM ≥ 10 kPa * Outpatient at the Clinical Department of Internal Medicine II, University Hospital St. Pölten * Signed patient consent form Exclusion Criteria: * Age older than 18 years * Pregnancy * Primary hepatic malignancy (hepatocellular carcinoma, cholangiocarcinoma) with portal invasion and/or extrahepatic spread

Treatments Being Tested

DIAGNOSTIC_TEST

hepatomiR

hepatomiR is a CE-certified test intended for gauging liver-related outcomes. It quantifies the levels of hsa-miR-122-5p, hsa-miR-192-5p, and hsa-miR-151a-5p in human plasma samples. A proprietary algorithm is then used to compute a liver function score (hepatomiR p-score).

Locations (1)

University Hospital St. Pölten

Sankt Pölten, Lower Austria, Austria