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RECRUITINGINTERVENTIONAL

Excess Base Comparison Between Pregnant Subjects With Severe Preeclampsia vs. Normotensive Pregnant Women

Comparison of Base Excess in Arterial Blood Gases Between Patients With Severe Preeclampsia and Normotensive Pregnant Patients

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The study's primary goal is to compare the base excess (BE) values-an indicator of metabolic changes-in two groups of patients at Santo Tomás Hospital: those with severe preeclampsia and healthy, pregnant individuals. Researchers will measure these values using an arterial blood gas test before delivery or surgery. This is a prospective cohort study. The researchers will analyze various blood gas parameters, including pH, lactate, and BE, and then correlate the BE values with clinical variables and negative maternal outcomes. The expected outcome is that a abnormal BE values will be linked to a greater severity of preeclampsia. If this association is confirmed, BE could serve as an additional marker for predicting the severity of the condition and may lay the groundwork for future research on diagnostic and therapeutic standards based on blood gas analysis.

Who May Be Eligible (Plain English)

Who May Qualify: - Gestational age: 24-40 weeks - Cases: Diagnosis of severe preeclampsia - Control: Normal blood pressure Who Should NOT Join This Trial: - Metabolic conditions that could hinder the results (diabetic ketoacidosis, sepsis, renal failure). - Clinical conditions that could hinder the results (diarrhea, vomit) - Recent use of bicarbonate Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Gestational age: 24-40 weeks * Cases: Diagnosis of severe preeclampsia * Control: Normal blood pressure Exclusion Criteria: * Metabolic conditions that could hinder the results (diabetic ketoacidosis, sepsis, renal failure). * Clinical conditions that could hinder the results (diarrhea, vomit) * Recent use of bicarbonate

Treatments Being Tested

DIAGNOSTIC_TEST

Arterial Blood gases

Determination of Excess Base in arterial blood gases before delivery / termination of pregnancy

Locations (1)

Saint Thomas Hospital
Panama City, Provincia de Panamá, Panama