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University of Chicago

18 clinical trials · 18 recruiting · OTHER

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by University of Chicago

RECRUITINGNCT06171269

Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to...

The purpose of this research is to gather information on the safety and effectiveness of using an imaging technique called magnetic resonance imaging (MRI) to decrease radiation...

Sponsor: University of ChicagoEnrolling: 601 location
Prostate Cancer
RECRUITINGNCT06898996

FITting Non-invasive Tests in Lynch Syndrome Surveillance

The purpose of this clinical study is to evaluate the accuracy of the fecal immunochemical test (FIT) in comparison to colonoscopy in patients with Lynch Syndrome (LS) who are...

Sponsor: University of ChicagoEnrolling: 4003 locations
Colorectal Cancer
RECRUITINGPhase 2NCT04515836

Olaparib in Patients With HRD Malignant Mesothelioma

In this study, researchers will give olaparib (a drug) to mesothelioma patients who have specific changes in their DNA (known as gene mutations). Researchers will give this drug...

Sponsor: University of ChicagoEnrolling: 561 location
MesotheliomaHomologous Recombination Deficiency
RECRUITINGNCT01416714

Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer,...

The purpose of this study is to collect and store normal and malignant tissue from patients with gastric cancer, GIST, esophageal cancer, pancreas cancer, hepatocellular cancer,...

Sponsor: University of ChicagoEnrolling: 10001 location
Gastric Cancers
RECRUITINGNCT07126509

Partial Pleurectomy (Surgery) for Unresectable Pleural Mesothelioma

Purpose of the study: The main purpose of this research study is to see if a surgery procedure (limited partial pleurectomy and decortication) helps symptoms in people who have...

Sponsor: University of ChicagoEnrolling: 301 location
MesotheliomaMesothelioma; LungMesotheliomas Pleural+2
RECRUITINGNCT05104710

Intermuscular Coherence as a Biomarker for ALS

The specific aims of this study are to: 1. Determine if a painless and quick measurement of muscle activity using surface electrodes can help with the diagnosis of ALS....

Sponsor: University of ChicagoEnrolling: 6504 locations
Amyotrophic Lateral Sclerosis
RECRUITINGNCT06966713

Predict Severe Traumatic Brain Injury

Severe traumatic brain injury (TBI) is associated with a 20-30% mortality rate and significant disability among most survivors. The Centers for Disease Control and Prevention...

Sponsor: University of ChicagoEnrolling: 1202 locations
Traumatic Brain Injury
RECRUITINGNCT06725108

Hemodynamic ABI Monitor

The goal of this observational study is to explore the relationship of heart function with the course and outcomes after traumatic brain injuries and nontraumatic intracerebral...

Sponsor: University of ChicagoEnrolling: 501 location
Traumatic Brain Injury (TBI)Intracerebral Hemorrhage
RECRUITINGNCT00138931

Genetics of Cardiovascular and Neuromuscular Disease

We are studying the genetics of human cardiovascular and neuromuscular disease. There are many different genetic regions that have been associated with the development of...

Sponsor: University of ChicagoEnrolling: 20001 location
CardiomyopathyArrhythmiaMuscular Dystrophy
RECRUITINGNCT06693310

STOP-UC: De-escalation of Therapy in Patients With Ulcerative Colitis With Histological Remission

The goal of this study is to better understand treatment strategies for people with ulcerative colitis (UC). Researchers will compare patients with UC in histologic remission (no...

Sponsor: University of ChicagoEnrolling: 2001 location
Ulcerative Colitis (UC)
RECRUITINGNCT05680012

Tissue Destruction and Healing in Celiac Disease

The purpose of this clinical study is to learn more about celiac disease pathogenesis and clinical symptoms. In particular, this study will examine the interactions between...

Sponsor: University of ChicagoEnrolling: 2203 locations
Celiac Disease
RECRUITINGNCT06317701

Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation

The purpose of this study is to determine if the treatment of Obstructive sleep apnea (OSA) by hypoglossal nerve stimulation (HGNS) will alter glucose metabolism. The study team...

Sponsor: University of ChicagoEnrolling: 301 location
Obstructive Sleep Apnea
RECRUITINGNCT00515567

Explanted Lung Tissues With Pulmonary Fibrosis

The goal of this study is to use the tissues from the explanted lungs in order to better study the cause of pulmonary fibrosis at a cellular level.

Sponsor: University of ChicagoEnrolling: 901 location
Pulmonary Fibrosis
RECRUITINGNCT00470327

A Study of the Natural Progression of Interstitial Lung Disease (ILD)

We propose to acquire data and blood samples on all patients being cared for by the Interstitial Lung Disease (ILD) program. Additionally, we will collect data and blood samples...

Sponsor: University of ChicagoEnrolling: 40001 location
Interstitial Lung DiseasesIdiopathic Pulmonary FibrosisSarcoidosis+1
RECRUITINGPhase 4NCT06008860

A Pilot Clinical Evaluation of Astepro® Nasal Spray for Management of Early SARS-CoV-2 Infection

The study team proposes to evaluate the efficacy of Astepro® 0.15% nasal spray in treating SARS-CoV-2 infection in adults through a pilot and feasibility clinical trial at the...

Sponsor: University of ChicagoEnrolling: 2801 location
COVID-19
RECRUITINGNCT01280825

The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing

The purpose of this study is to collect DNA samples from patients undergoing routine care at the University of Chicago. These samples will be tested for differences in genes that...

Sponsor: University of ChicagoEnrolling: 12001 location
Patients Undergoing Routine Health CareHeart DiseasesInflammatory Bowel Diseases+5
RECRUITINGNCT06417762

Dime La VerDAD: Verify, Debunk, and Disseminate

Dime la Verdad (Tell me the truth) will evaluate the use of storytelling by community health workers as a communication strategy to disseminate reliable health information on...

Sponsor: University of ChicagoEnrolling: 14004 locations
InfluenzaCOVID-19Communication Research+2
RECRUITINGPhase 2NCT05640271

Tocilizumab for Acute Chest Syndrome

The investigators are evaluating the role of a low dose of tocilizumab in treating acute chest syndrome in patients with sickle cell disease. Tocilizumab inhibits interleukin-6...

Sponsor: University of ChicagoEnrolling: 2001 location
Sickle Cell DiseaseAcute Chest Syndrome