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Eli Lilly and Company

15 clinical trials · 15 recruiting · INDUSTRY

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by Eli Lilly and Company

RECRUITINGPhase 1 / Phase 2NCT04956640

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

The purpose of this study is to find out whether the study drug, LY3537982, is safe and effective in cancer patients who have a specific genetic mutation (KRAS G12C). Patients...

Sponsor: Eli Lilly and CompanyEnrolling: 54020 locations
Carcinoma, Non-Small-Cell LungColorectal NeoplasmsEndometrial Neoplasms+3
RECRUITINGPhase 3NCT07213804

A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and...

This is a clinical study that has two parts. It is testing a potential new medicine called Sofetabart Mipitecan (LY4170156) for people with certain types of ovarian, peritoneal,...

Sponsor: Eli Lilly and CompanyEnrolling: 108020 locations
Ovarian NeoplasmsFallopian Tube NeoplasmsPeritoneal Neoplasms+1
RECRUITINGPhase 1NCT07100119

A Study of LY4256984 in Participants With Sporadic Amyotrophic Lateral Sclerosis

The purpose of this study is to evaluate how well LY4256984 is tolerated and what side effects may occur in participants with sporadic amyotrophic lateral sclerosis (ALS). The...

Sponsor: Eli Lilly and CompanyEnrolling: 3212 locations
ALS (Amyotrophic Lateral Sclerosis)
RECRUITINGPhase 3NCT07241390

A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease...

The purpose of this study is to measure cardiovascular outcomes with orforglipron compared with placebo in participants with atherosclerotic cardiovascular disease (ASCVD) and/or...

Sponsor: Eli Lilly and CompanyEnrolling: 714020 locations
Atherosclerosis Cardiovascular DiseaseChronic Kidney Disease
RECRUITINGPhase 3NCT07223593

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

The purpose of this study is to evaluate the effect and safety of orforglipron once daily in participants with Fontaine II peripheral arterial disease (PAD). Participation in the...

Sponsor: Eli Lilly and CompanyEnrolling: 120520 locations
Peripheral Arterial Disease
RECRUITINGPhase 2NCT07286175

A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)

The purpose of this study is to assess the efficacy and safety of brenipatide when administered with standard of care (SoC), compared with placebo plus SoC in delaying the...

Sponsor: Eli Lilly and CompanyEnrolling: 40020 locations
Bipolar Disorder
RECRUITINGPhase 3NCT05509777

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

Study participants will be screened during the platform study and randomly assigned to receive mirikizumab or another intervention. The purpose of the mirikizumab study is to...

Sponsor: Eli Lilly and CompanyEnrolling: 9020 locations
Crohn's Disease
RECRUITINGPhase 3NCT06937086

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active...

The main purpose of this study is to show whether in these individuals, treatment with both mirikizumab and tirzepatide, compared with treatment with mirikizumab and placebo,...

Sponsor: Eli Lilly and CompanyEnrolling: 35020 locations
Ulcerative ColitisObesity or Overweight
RECRUITINGPhase 2NCT07186101

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

The main purpose of the study is to evaluate the effectiveness and safety of LY4268989 when given with mirikizumab compared to mirikizumab alone in adult participants with...

Sponsor: Eli Lilly and CompanyEnrolling: 25220 locations
Ulcerative Colitis
RECRUITINGPhase 4NCT06864026

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active...

The main purpose of this study is to assess the effectiveness of adding tirzepatide to ixekizumab therapy in standard clinical practice in participants with moderate-to-severe PsA...

Sponsor: Eli Lilly and CompanyEnrolling: 20020 locations
Psoriatic ArthritisOverweight or Obesity
RECRUITINGPhase 1NCT06280703

A Study of LY3938577 in Healthy Participants and Participants With Type 1 Diabetes Mellitus (T1DM)

The main purpose of this study is to look at the amount of the study drug LY3938577 that gets into the blood stream and how long it takes the body to get rid of it. At a later...

Sponsor: Eli Lilly and CompanyEnrolling: 1181 location
HealthyType 1 Diabetes Mellitus
RECRUITINGPhase 3NCT06993792

A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2...

The purpose of this Master Protocol is to support two studies to see how well and how safely orforglipron works compared to placebo in participants who have obesity or overweight...

Sponsor: Eli Lilly and CompanyEnrolling: 120020 locations
ObesityOverweightType 2 Diabetes
RECRUITINGPhase 1NCT06945419

A Study of LY4086940 in Healthy Participants and Participants With Overweight or Obesity, With or Without Type 2...

The main purpose of this study is to evaluate the safety, tolerability of LY4086940 and how it is processed in the body. Participation in Part A of the study will last about 10...

Sponsor: Eli Lilly and CompanyEnrolling: 2165 locations
HealthyOverweightObesity+1
RECRUITINGPhase 3NCT07321886

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

The purpose of this study is to evaluate the efficacy and safety of eloralintide in adults with obesity or overweight who do not have type 2 diabetes. The study has two phases: a...

Sponsor: Eli Lilly and CompanyEnrolling: 198020 locations
ObesityOverweight
RECRUITINGPhase 3NCT05508789

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

The reason for this study is to assess the safety and efficacy of donanemab in participants with early Alzheimer's disease. The study duration including screening and follow-up is...

Sponsor: Eli Lilly and CompanyEnrolling: 150020 locations
Alzheimer DiseaseDementiaBrain Diseases+6