Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

Who May Qualify: - Have symptomatic PAD with intermittent claudication of Fontaine Stage II - Have an Ankle Brachial Index (ABI) of 0.9 or less Who Should NOT Join This Trial: - Have a body mass index (BMI) less than 23 kilogram per square meter (kg/m2) - Have Hemoglobin A1c (HbA1c) greater than 10% - Have walking ability limited by conditions other than PAD - Have a planned lower limb surgery or any other surgery affecting walking ability - Had peripheral revascularization procedure within 90 days prior to the day of screening or planning to undergo peripheral revascularization during the clinical trial - Had stroke, transient ischemic attack, myocardial infarction, coronary or carotid revascularization, or hospitalization for unstable angina pectoris within 60 days prior to screening - Have heart failure presently classified as being in New York Heart Association class III - IV Always talk to your doctor about whether this trial is right for you.