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AbbVie

30 clinical trials · 30 recruiting · INDUSTRY

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by AbbVie

RECRUITINGPhase 2 / Phase 3NCT07095452

A Study to Assess A Change in Disease Activity and Adverse Events of Intravenous Etentamig and Daratumumab...

Multiple myeloma (MM) is a cancer of the blood's plasma cells. The cancer is typically found in the bones and bone marrow (the spongy tissue inside of the bones) and can cause...

Sponsor: AbbVieEnrolling: 66020 locations
Multiple Myeloma
RECRUITINGPhase 1NCT07409246

A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves...

Multiple myeloma (MM) is a plasma cell disease characterized by the growth of clonal plasma cells in the bone marrow. The purpose of this study is to assess the safety,...

Sponsor: AbbVieEnrolling: 1271 location
Multiple Myeloma
RECRUITINGPhase 1 / Phase 2NCT06953960

A Study to Assess Adverse Events and Change in Disease Activity of Oral ABBV-453 Alone or in Combination With...

Multiple myeloma (MM) is a plasma cell disease characterized by the growth of clonal plasma cells in the bone marrow. The purpose of this study is to assess the safety and change...

Sponsor: AbbVieEnrolling: 13020 locations
Multiple Myeloma
RECRUITINGNCT06965374

Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants With Advanced...

Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot from person to person. Some...

Sponsor: AbbVieEnrolling: 27019 locations
Parkinson Disease
RECRUITINGNCT05916157

An Observational Study of Subcutaneous Infusion of ABBV-951 to Assess Change in Disease Activity and Adverse Events In...

Parkinson's disease (PD) is a neurological condition, which affects the brain. Some symptoms of PD are tremors, stiffness, and slowness of movement. The purpose of this study is...

Sponsor: AbbVieEnrolling: 25016 locations
Parkinson's Disease (PD)
RECRUITINGPhase 3NCT06241313

Study of Oral Atogepant Tablets to Assess Safety and Efficacy in Adult Participants With Migraine

A migraine attack is a moderate or severe headache that usually occurs on one side of the head and is often accompanied by throbbing, sensitivity to light, sensitivity to sound,...

Sponsor: AbbVieEnrolling: 130020 locations
Migraine
RECRUITINGPhase 2NCT06602479

A Study to Investigate the Safety and Efficacy of MEDI0618 Compared to Placebo in Adult Participants With Episodic...

The purpose of this Phase 2 study is to evaluate the safety and efficacy of SC MEDI0618 compared to placebo in participants with episodic migraine.

Sponsor: AbbVieEnrolling: 48820 locations
Migraine
RECRUITINGNCT07310290

Study to Assess the Real-World Effectiveness of Ubrogepant in Adult Participants When Treating During the Prodrome...

Migraine is a neurological disease characterized by moderate or severe headaches, associated with nausea, vomiting, and/or sensitivity to light and sound. This study will assess...

Sponsor: AbbVieEnrolling: 1893 locations
Migraine
RECRUITINGNCT06603558

Post-Marketing Study to Assess the Safety and Effectiveness of Oral Atogepant in Korean Adult Participants for the...

Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound. The study will assess the...

Sponsor: AbbVieEnrolling: 30004 locations
Chronic MigraineEpisodic MigraineMigraine
RECRUITINGPhase 3NCT06810505

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in...

Migraine is a disease that most often causes moderate to severe headache on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea,...

Sponsor: AbbVieEnrolling: 42020 locations
Chronic Migraine
RECRUITINGPhase 3NCT05711394

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants...

A migraine is a moderate to severe headache on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea, vomiting, sensitivity to light...

Sponsor: AbbVieEnrolling: 45020 locations
Episodic Migraine
RECRUITINGNCT05158894

Observational Study to Assess Adverse Events When Adult Female Participants Are Treated With Ubrelvy (Ubrogepant) or...

Migraine is a common neurological disorder typically characterized by attacks of throbbing or pulsating headache on one side of the head of moderate to severe pain intensity. The...

Sponsor: AbbVieEnrolling: 18842 locations
Migraine
RECRUITINGNCT06543914

Observational Study of Oral Atogepant to Evaluate Real-World Effectiveness in Adult Participants With Migraine

Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound. This study will evaluate...

Sponsor: AbbVieEnrolling: 100020 locations
Migraine
RECRUITINGPhase 3NCT05125302

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in...

Migraine is a common neurological disorder typically characterized by attacks of throbbing, moderate to severe headache, often associated with nausea, vomiting, and sensitivity to...

Sponsor: AbbVieEnrolling: 105920 locations
Migraine
RECRUITINGPhase 3NCT06417775

Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual...

A migraine is a moderate to severe headache typically on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea, vomiting, sensitivity...

Sponsor: AbbVieEnrolling: 49620 locations
Migraine
RECRUITINGNCT06712628

A Comparison Study of Persistence of UPadacitinib vs. TNF-inhibitoRs In a German Real-world SettING

This study will compare the retention rates for UPA vs. TNFi treatment in adult participants with moderate to severe active RA per local label and according to local standard of...

Sponsor: AbbVieEnrolling: 67820 locations
Moderate to Severe Rheumatoid Arthritis
RECRUITINGPhase 3NCT05843643

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With...

Systemic Lupus Erythematosus (SLE) is an immune-mediated disease associated with inflammation of multiple organ systems. This study will assess how safe and effective upadacitinib...

Sponsor: AbbVieEnrolling: 100020 locations
Systemic Lupus Erythematosus
RECRUITINGPhase 3NCT06332534

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to...

Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tract, most often affecting the bowels. It can cause many...

Sponsor: AbbVieEnrolling: 11020 locations
Crohn's Disease
RECRUITINGNCT06764706

Study to Assess Change in Disease Activity of Risankizumab Treatment in Adult Participants With Moderate to Severe...

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine). This study will...

Sponsor: AbbVieEnrolling: 20020 locations
Ulcerative Colitis
RECRUITINGNCT05496348

Study of Oral Upadacitinib to Assess Change in Disease Activity in Adult Participants With Ulcerative Colitis

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine).This study will...

Sponsor: AbbVieEnrolling: 40020 locations
Ulcerative Colitis
RECRUITINGNCT07039110

Study to Assess Change in Quality of Life of Risankizumab Treatment in Adult Participants With Moderate-to-Severe...

Psoriasis is a chronic, systemic, inflammatory disease in which skin cells build up and develop thick, red and white scaly patches on the skin. This study will assess the change...

Sponsor: AbbVieEnrolling: 70020 locations
Plaque Psoriasis
RECRUITINGNCT06764693

An Ex-US Study to Assess Treatment Persistence With Risankizumab in Adult Participants With Psoriatic Arthritis

Psoriatic arthritis (PsA) is a type of arthritis (swelling and stiffness in the joints) that is frequently seen in trial participants who also have the skin condition psoriasis....

Sponsor: AbbVieEnrolling: 120020 locations
Psoriatic Arthritis
RECRUITINGPhase 2NCT06865105

Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis

Psoriatic arthritis (PsA) is a type of arthritis that happens when the body's immune system attacks healthy cells and tissues causing joint pain, stiffness, and swelling. Symptoms...

Sponsor: AbbVieEnrolling: 12020 locations
Psoriatic Arthritis
RECRUITINGNCT07419347

Study of Glecaprevir/Pibrentasvir to Assess Safety Through Real-World Data

The objective of this study is to assess the safety, tolerability and effectiveness of 8-week Glecaprevir/Pibrentasvir (G/P) in participants taking either prescribed or illicit...

Sponsor: AbbVieEnrolling: 20002 locations
Hepatitis C Virus (HCV)
RECRUITINGPhase 2 / Phase 3NCT04704921

Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in...

ABBV-RGX-314 (also known as RGX-314) is being developed as a novel one-time gene therapy for the treatment of neovascular (wet) age-related macular degeneration (wet AMD or nAMD)....

Sponsor: AbbVieEnrolling: 63020 locations
AMDnAMDWet Age-related Macular Degeneration+6
RECRUITINGPhase 3NCT05407636

Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

ABBV-RGX-314 (also known as RGX-314) is being developed as a novel one-time gene therapy for the treatment of neovascular (wet) age-related macular degeneration (wet AMD). Wet AMD...

Sponsor: AbbVieEnrolling: 66020 locations
AMDnAMDWet Age-related Macular Degeneration+3
RECRUITINGPhase 1 / Phase 2NCT07160179

Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With...

Age-related macular degeneration (AMD) is the abnormal growth of new blood vessels in the light-sensitive tissue at the back of the eye called the retina. Geographic Atrophy (GA)...

Sponsor: AbbVieEnrolling: 664 locations
Geographic AtrophyAge-Related Macular Degeneration
RECRUITINGPhase 4NCT05821855

A Study to Evaluate Adverse Events and Change in Disease Activity With the XEN45 Glaucoma Treatment System Implantation...

Glaucoma is the second most common cause of blindness in the world, second only to cataracts. The purpose of this study is to assess adverse events (AEs) and changes in disease...

Sponsor: AbbVieEnrolling: 13013 locations
Open-angle GlaucomaOAG
RECRUITINGPhase 3NCT07284381

A Clinical Study to Evaluate the Effect and Side Effect of a New Artificial Tear Formulation (ABBV-444) Compared to...

Dry Eye Disease (DED) refers to a long-term condition that happens when there is not enough lubrication in your eyes. This can happen when your eye cannot make enough tears or if...

Sponsor: AbbVieEnrolling: 25020 locations
Dry Eye Disease
RECRUITINGPhase 1NCT06977724

A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of...

Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease characterized by B cell hyperactivity and Sjorgren's disease (SjD) is a chronic, multisystem...

Sponsor: AbbVieEnrolling: 366 locations
Dry Eye SyndromeSystemic Lupus Erythematosus