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Neovascular Age-related Macular Degeneration Clinical Trials

10 recruiting trials for Neovascular Age-related Macular Degeneration. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
10
Total Trials
10
Recruiting Now
2
Phase 3 Trials
9
Sponsors

Recruiting Trials

RECRUITINGPhase 3NCT05904028

Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD

Home optical coherence tomography- guided treatment versus treat and extend for the management of neovascular age-related macular degeneration.

Sponsor: Jaeb Center for Health ResearchEnrolling: 60020 locations
RECRUITINGPhase 2 / Phase 3NCT04704921

Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in...

ABBV-RGX-314 (also known as RGX-314) is being developed as a novel one-time gene therapy for the treatment of neovascular (wet) age-related macular degeneration (wet AMD or nAMD)....

Sponsor: AbbVieEnrolling: 63020 locations
RECRUITINGNCT06439576

Real World Evidence in China: Faricimab Use in Diabetic Macular Edema, Retinal Vein Occlusion, and Neovascular...

The Farseeing Study will explore long-term effectiveness, safety, and treatment patterns among patients being treated with faricimab in real-world, routine clinical practice in...

Sponsor: Hoffmann-La RocheEnrolling: 100020 locations
RECRUITINGEarly Phase 1NCT07053358

Safety and Efficacy Evaluation of LX111 Gene Therapy in nAMD Patients

The goal of this study is to evaluate the safety and efficacy of LX111 treatment of nAMD. This study will enroll subjects aged ≥ 50 vears old to receive a single unilateral...

Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineEnrolling: 101 location
RECRUITINGPhase 1 / Phase 2NCT06141460

Safety and Efficacy of RRG001 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

A Phase I/IIa, Dose-escalation and Dose-expansion Study to Evaluate the Safety and Efficacy of Single Subretinal Injection of RRG001 in Subjects With Neovascular Age-related...

Sponsor: Shanghai Refreshgene Technology Co., Ltd.Enrolling: 481 location
RECRUITINGPhase 1 / Phase 2NCT06660667

A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular Degeneration

This is a Phase 1/Phase 2 multicenter study to evaluate the safety and efficacy of a one-time single-eye intravitreal dose of SAR402663 in participants with neovascular...

Sponsor: SanofiEnrolling: 6618 locations
RECRUITINGNCT04985487

Regulatory Post-Marketing Surveillance Study for Brolucizumab

This study is an open-label, multicenter, single-arm, observational post-marketing surveillance.

Sponsor: Novartis PharmaceuticalsEnrolling: 300020 locations
RECRUITINGPhase 1NCT06213038

A Clinical Study Evaluating the Safety and Efficacy of SKG0106 in Patients With Neovascular Age-related Macular...

This is a clinical study to evaluate the safety, preliminary efficacy, immunogenicity of SKG0106 in subjects with nAMD.

Sponsor: Youxin ChenEnrolling: 123 locations
RECRUITINGPhase 3NCT03683251

Extension Study for the Port Delivery System With Ranibizumab (Portal)

This study will evaluate the long-term safety and tolerability of the Port Delivery System with ranibizumab (PDS) (100 mg/mL) in participants with neovascular age-related macular...

Sponsor: Hoffmann-La RocheEnrolling: 100020 locations
RECRUITINGPhase 2NCT07275840

A Study to Evaluate the Efficacy and Safety of IBI302inSubjects With nAMD

This study is designed for Open-label, multi-center, single-arm Phase II trail to evaluate the efficacy and safety of intravitreal injection of IBI302 in nAMD patients.

Sponsor: Innovent Biologics Technology Limited (Shanghai R&D Center)Enrolling: 8001 location