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Real World Evidence in China: Faricimab Use in Diabetic Macular Edema, Retinal Vein Occlusion, and Neovascular Age-Related Macular Degeneration (The Farseeing Study)

China Faricimab Real World Evidence: Evaluation of Faricimab Effectiveness, Safety and Treatment Pattern, in Diabetic Macular Edema, Retinal Vein Occlusion and Neovascular Age-Related Macular Degeneration: The Farseeing Study

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The Farseeing Study will explore long-term effectiveness, safety, and treatment patterns among patients being treated with faricimab in real-world, routine clinical practice in China. It is a primary data collection, non-interventional, prospective and retrospective, multi-center study designed to collect real-world, long-term data to gain clinical evidence on faricimab, by observing cohorts of patients with neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), and retinal vein occlusion (RVO) who are receiving treatment with faricimab.

Who May Be Eligible (Plain English)

Who May Qualify: 1. Have signed the willing to sign a consent form 2. Female and male Chinese patients, who had been diagnosed with nAMD, DME, or RVO by CFP, OCT, FFA, ICGA, or OCTA 3. ≥50 years old for patients with nAMD, ≥18 years old both for patients with DME and RVO, at the time of signing willing to sign a consent form (or the first administration of faricimab, whichever occurs first) 4. Patients for whom the decision to receive treatment with faricimab is made prior to and independent from study participation 5. Patients have received at least one faricimab treatment (the first dose) in the study eye Who Should NOT Join This Trial: 1. Patients not receiving treatment for nAMD/DME/RVO with faricimab according to the standard of care and in line with the current summary of product characteristics (SPC) / labeling in China 2. Active ocular inflammation or suspected / active ocular infection in either eye 3. Received any other anti-VEGF treatment after faricimab 4. Received any steroid treatment within 6 months (180 days) before the first faricimab treatment in the study eye 5. Any participation in any other clinical trials currently 6. Patients could not provide the clinical data (visual acuity and OCT images) within 2 weeks (14 days) before receiving the initial faricimab injection Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: 1. Have signed the informed consent 2. Female and male Chinese patients, who had been diagnosed with nAMD, DME, or RVO by CFP, OCT, FFA, ICGA, or OCTA 3. ≥50 years old for patients with nAMD, ≥18 years old both for patients with DME and RVO, at the time of signing informed consent (or the first administration of faricimab, whichever occurs first) 4. Patients for whom the decision to receive treatment with faricimab is made prior to and independent from study participation 5. Patients have received at least one faricimab treatment (the first dose) in the study eye Exclusion Criteria: 1. Patients not receiving treatment for nAMD/DME/RVO with faricimab according to the standard of care and in line with the current summary of product characteristics (SPC) / labeling in China 2. Active ocular inflammation or suspected / active ocular infection in either eye 3. Received any other anti-VEGF treatment after faricimab 4. Received any steroid treatment within 6 months (180 days) before the first faricimab treatment in the study eye 5. Any participation in any other clinical trials currently 6. Patients could not provide the clinical data (visual acuity and OCT images) within 2 weeks (14 days) before receiving the initial faricimab injection

Treatments Being Tested

DRUG

Faricimab

The dosing and treatment duration of the studied medicinal product is at the discretion of the physician in accordance with clinical practice and labeling in China.

Locations (20)

Joint Shantou International Eye Center
Shantou, Guangdong, China
The First Affiliated Hospital of Henan UN of Science and Technology
Luoyang, Henan, China
Taihe Hospital of Shiyan
Shiyan, Hubei, China
Xuzhou No.1 Peoples Hospital
Xuzhou, Jiangsu, China
Fushun Eye Hospital
Fushun, Liaoning, China
Panjin Central Hospital
Panjin, Liaoning, China
The First Hospital of China Medical University
Shenyang, Liaoning, China
Affiliated Hospital of Shandong Second Medical University
Weifang, Shandong, China
Shanghai General Hospital
Shanghai, Shanghai Municipality, China
The First People's Hospital of Chengdu
Chengdu, Sichuan, China
The First People's Hospital of Kashgar
Kashgar, Xinjiang Uygur, China
The First People's Hospital of Yunnan Province
Kunming, Yun'nan, China
Jinhua municipal central hospital
Jinhua, Zhejiang, China
Peking University People's Hospital
Beijing, China
Sichuan Provincial People's Hospital
Chengdu, China
People's Hospital of Dingzhou
Dingzhou, China
Dongyang People's Hospital
Dongyang, China
Zhongshan Ophthalmic Center, Sun Yat-sen University
Guangzhou, China
Guizhou Provincial People's Hospital
Guiyang, China
Eye Hospital of Shandong First Medical University
Jinan, China