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RECRUITINGINTERVENTIONAL

Effects of Beetroot Extract on Blood Pressure and Exercise in Hypertensive Older Women

Acute Effects of Beetroot Extract Supplementation on Blood Pressure, Oxidative Stress, and Muscle Oxygen Saturation in Hypertensive Older Women Submitted to an Aerobic Exercise Session

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The goal of this clinical trial is to learn about the acute effects of beetroot extract in older women with high blood pressure. The main questions it aims to answer are: Does beetroot extract affect blood pressure during exercise? Does it change oxygen levels in the muscles? Participants will take a beetroot supplement and perform an aerobic exercise session to check how their bodies respond.

Who May Be Eligible (Plain English)

Who May Qualify: - Female sex: Older women aged between 60 and 70 years. - Physical capability: Absence of health conditions that could compromise performance in the required physical exercise tests. Who Should NOT Join This Trial: - Smoking: Current smokers. - Alcohol use: History of alcohol abuse or excessive alcohol consumption. - Cardiovascular Disease: Diagnosis of cardiovascular diseases (other than the primary condition of hypertension). Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Female sex: Older women aged between 60 and 70 years. * Physical capability: Absence of health conditions that could compromise performance in the required physical exercise tests. Exclusion Criteria: * Smoking: Current smokers. * Alcohol use: History of alcohol abuse or excessive alcohol consumption. * Cardiovascular Disease: Diagnosis of cardiovascular diseases (other than the primary condition of hypertension).

Treatments Being Tested

DIETARY_SUPPLEMENT

Beetroot Extract (Nitrate-rich)

Participants will ingest 2 capsules of a standardized beetroot extract (Berkeley Life Nitric Oxide Foundation). Each dose provides approximately 314 mg of dietary nitrate.

DIETARY_SUPPLEMENT

Placebo

Capsules identical in appearance, color, and size to the experimental supplement, but containing an inert substance (starch). This intervention is used to maintain the double-blind design of the study.

BEHAVIORAL

Exercise

Participants will perform a single aerobic exercise session on a treadmill. The protocol consists of a 7-minute warm-up followed by 30 minutes of continuous exercise at an intensity corresponding to 60-80% of maximum heart rate (HRmax), estimated using Tanaka's formula (208 - 0.7 \* age). Rate of Perceived Exertion (RPE) will be monitored periodically using the Borg scale (6-20).

OTHER

Rest (Control Condition)

Participants will remain seated for 30 minutes (matching the exercise session duration). During this time, a researcher will administer a Food Frequency Questionnaire (FFQ) in an interview format. This activity serves to assess dietary habits and simulates a routine, low-exertion daily activity (similar to a conversation), acting as a time-matched control for the exercise session.

Locations (1)

São Paulo State University (UNESP)
Bauru, São Paulo, Brazil