RECRUITINGOBSERVATIONAL
Study on Blood Pressure Variability and Frailty in the Older People
Study on Blood Pressure Variability and Frailty in the Older People: the HypoPHrail Study
About This Trial
Observational prospective single-center, non-profit study. Primary objective of the study: To determine if the hypotensive phenotype, defined as one episode of daytime systolic blood pressure (SBP) \<90 mmHg (or two episodes of daytime SBP \<90 mmHg, if mean 24 h SBP is \<125 mmHg) detected at Ambulatory Blood Pressure Monitoring (ABPM) is associated with adverse events at follow up (death, hospitalization, falls, emergency room admission for uncontrolled hypertension, major cardiovascular events)
Who May Be Eligible (Plain English)
Who May Qualify:
- Age ≥ 75 years
- Diagnosis of hypertension according to the criteria of the European Society of Cardiology guidelines \[Williams 2018\]
- Consent of the patient (or legal representative) to participate in the study
Who Should NOT Join This Trial:
- Refusal of the patient or his/her legal representative
- Life expectancy of less than 6 months
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Age ≥ 75 years
* Diagnosis of hypertension according to the criteria of the European Society of Cardiology guidelines \[Williams 2018\]
* Consent of the patient (or legal representative) to participate in the study
Exclusion Criteria:
* Refusal of the patient or his/her legal representative
* Life expectancy of less than 6 months
Treatments Being Tested
DIAGNOSTIC_TEST
Diagnostic tests and questionnaires
Assessment of office blood pressure, orthostatic hypotension, 24-hour ambulatory blood pressure, frailty
Locations (1)
Istituto Auxologico Italiano IRCCS
Milan, Italy