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RECRUITINGOBSERVATIONAL

Imaging the Pathogenesis of Cerebral Small Vessel Disease

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Cerebral small vessel disease (CSVD) can lead to vascular cognitive impairment and dementia (VCID). The hallmark of CSVD is the appearance and progression of white matter hyperintensities (WMH) on MRI. The goal of this study it to recruit and follow individuals at risk for WMH progression and use serial MRI scanning to gain insights into the pathogenesis of CSVD.

Who May Be Eligible (Plain English)

Who May Qualify: - Clinical or radiographic evidence of ischemic stroke - One vascular risk factor (hypertension, hyperlipidemia, or diabetes) - Evidence of cerebral small vessel disease on MRI Who Should NOT Join This Trial: - Inability to complete 3 research MRI scans over 1.25 years Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Clinical or radiographic evidence of ischemic stroke * One vascular risk factor (hypertension, hyperlipidemia, or diabetes) * Evidence of cerebral small vessel disease on MRI Exclusion Criteria: * Inability to complete 3 research MRI scans over 1.25 years

Locations (1)

Kennedy Krieger Institute
Baltimore, Maryland, United States