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Retinal Degeneration Clinical Trials

10 recruiting trials for Retinal Degeneration. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
10
Total Trials
10
Recruiting Now
1
Phase 3 Trials
8
Sponsors

Recruiting Trials

RECRUITINGNCT04129021

High Resolution, High-speed Multimodal Ophthalmic Imaging

Knowledge of the pathogenesis of ocular conditions, a leading cause of blindness, has benefited greatly from recent advances in ophthalmic imaging. However, current clinical...

Sponsor: Centre Hospitalier National d'Ophtalmologie des Quinze-VingtsEnrolling: 12001 location
RECRUITINGNCT02617966

Rod and Cone Mediated Function in Retinal Disease

Background: Retinal diseases cause the loss of rod and cone photoreceptors. Symptoms include vision loss and night blindness. Researchers want to learn about rod and cone...

Sponsor: National Eye Institute (NEI)Enrolling: 5001 location
RECRUITINGNCT01432847

Cell Collection to Study Eye Diseases

Background: \- Best Vitelliform Dystrophy (Best disease), Late-Onset Retinal Degeneration (L-ORD), and Age-Related Macular Degeneration (AMD) all affect the retina, the light...

Sponsor: National Eye Institute (NEI)Enrolling: 9301 location
RECRUITINGNCT05355415

Adaptive Optics Imaging of Outer Retinal Diseases

The objective of the study is to collect adaptive optics (AO) retinal images from human subjects with outer retinal diseases (diseases of the outer retina including photoreceptor,...

Sponsor: Food and Drug Administration (FDA)Enrolling: 1002 locations
RECRUITINGPhase 2NCT07174687

SGLT2 Inhibitors in Geographic Atrophy

AMD is a leading cause of blindness in individuals over 50 years old, with dry AMD being the most common form. Geographic atrophy (GA) is an advanced stage of dry AMD...

Sponsor: Washington University School of MedicineEnrolling: 701 location
RECRUITINGPhase 3NCT06305416

A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema

Macular edema in diabetes, defined as retinal thickening within two disc diameters of the center of the macula, results from retinal microvascular changes that compromise the...

Sponsor: Incepta Pharmaceuticals LtdEnrolling: 701 location
RECRUITINGPhase 1 / Phase 2NCT05474729

Minocycline for Chronic Autoimmune Uveitis

Autoimmune uveitis is one kind of non-infectious, sight-threatening, relapsing and severe ocular disease. Approximately 20%-25% autoimmune uveitis patients suffer from the dilemma...

Sponsor: Sun Yat-sen UniversityEnrolling: 101 location
RECRUITINGPhase 1NCT06455826

MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)

A Phase 1 Open-Label, Multiple Ascending Dose Study to Evaluate the Safety and Tolerability of Intravitreally Administered VP-001 in Participants with Confirmed PRPF31...

Sponsor: PYC TherapeuticsEnrolling: 125 locations
RECRUITINGPhase 1 / Phase 2NCT06789445

A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)

Study OpCT-001-101 is a Phase 1/2a first-in-human, multisite, 2-part interventional study to evaluate the safety, tolerability, and the effect on clinical outcomes of OpCT-001 in...

Sponsor: BlueRock TherapeuticsEnrolling: 543 locations
RECRUITINGPhase 1 / Phase 2NCT06852963

A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in...

This is a Phase 1/2 repeat-dose, open-label, two-arm, parallel group safety and efficacy study of two doses of VP-001 (30 μg and 75 μg) in participants with confirmed PRPF31...

Sponsor: PYC TherapeuticsEnrolling: 166 locations