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Bipolar Depression Clinical Trials

14 recruiting trials for Bipolar Depression. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
14
Total Trials
14
Recruiting Now
3
Phase 3 Trials
10
Sponsors

Recruiting Trials

RECRUITINGNCT06370988

Theta-Burst Stimulation for Bipolar Depression

The purpose of this trial is to determine if intermittent theta-burst stimulation (iTBS) can reduce the symptoms of depression in treatment-resistant bipolar disorder. To do this,...

Sponsor: Centre for Addiction and Mental HealthEnrolling: 1242 locations
RECRUITINGNCT04664257

Delivering Electronic Cognitive Behavioural Therapy to Patients With Bipolar Disorder and Residual Depressive Symptoms

The lifetime prevalence of Bipolar II is 0.4% with the time spent with depressive symptoms outnumbering the time spent with hypomanic symptoms by 35 to 1. Regarding current...

Sponsor: Dr. Nazanin AlaviEnrolling: 801 location
RECRUITINGNCT06022913

Behavioural Activation for Bipolar Depression

Bipolar disorder (BD) affects between 1-3% of the world's population. People with BD experience episodes of mania or hypomania and in most cases, they experience periods of...

Sponsor: Reykjavik UniversityEnrolling: 101 location
RECRUITINGPhase 3NCT05603104

Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a...

Schizophrenia, bipolar and major depressive disorders collectively affect over 10 million people across the EU and are associated with annual healthcare and societal costs in...

Sponsor: Dr. Inge WinterEnrolling: 12541 location
RECRUITINGPhase 4NCT06417437

Non-invasive BCI and Application Verification for Depressed People

Major Depressive Disorder (MDD) is a serious mental illness and public health problem that poses threat to both physical and mental health. According to statistics from WHO, it is...

Sponsor: Shanghai Mental Health CenterEnrolling: 4001 location
RECRUITINGPhase 3NCT07172516

A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder...

X-CEED is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of azetukalner in adult participants diagnosed with...

Sponsor: Xenon Pharmaceuticals Inc.Enrolling: 40020 locations
RECRUITINGPhase 4NCT07266545

RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)

The purpose of this research is to understand how changes in RNA editing relate to treatment response in unipolar and bipolar depression.

Sponsor: Mayo ClinicEnrolling: 1201 location
RECRUITINGPhase 3NCT04569448

Brexpiprazole Treatment for Bipolar I Depression

Bipolar disorder (BD) is a frequent and lifelong recurrent mood disorder with treatment-resistant depressive episodes. Importantly, depressive symptoms and cognitive decline are...

Sponsor: Douglas Mental Health University InstituteEnrolling: 583 locations
RECRUITINGNCT04480918

University of Iowa Interventional Psychiatry Service Patient Registry

The purpose of this study is to examine the effects of interventional/procedural therapies for treatment-resistant depression (TRD) and Obsessive-Compulsive Disorder (OCD). These...

Sponsor: Mark NiciuEnrolling: 10001 location
RECRUITINGNCT07121894

Ketogenic Intervention for Bipolar Depression

The purpose of this study is to assess the clinical correlates of therapeutic precision ketosis in bipolar depression and to evaluate the cardiometabolic correlates associated...

Sponsor: Mayo ClinicEnrolling: 301 location
RECRUITINGNCT06488573

PROgram To Enhance Cardiovascular Risk Trough an Intervention of Nutrition in Bipolar Disorder

Individuals with Bipolar Disorder (BD) have twice the risk of being affected by metabolic comorbidities and a 1.8-fold increased risk of mortality from cardiovascular diseases...

Sponsor: University of Sao PauloEnrolling: 881 location
RECRUITINGNCT06524505

Efficacy, Tolerability, and Cognitive Effects of Deep Transcranial Magnetic Stimulation for Bipolar Depression

The aim of this study is to evaluate the feasibility and efficacy of deep transcranial magnetic stimulation (dTMS) as an add-on treatment for bipolar depression. Meanwhile, we aim...

Sponsor: Tianjin Anding HospitalEnrolling: 1001 location
RECRUITINGNCT06599099

Deep Brain Stimulation of Treatment-Resistant Bipolar Depression

This study is only enrolling at Baylor College of Medicine. The other research locations listed serve to support data analysis only. This research study is to investigate the use...

Sponsor: Wayne Goodman MDEnrolling: 104 locations
RECRUITINGNCT05384405

aiTBS for Relieving NSSI in Depressive Patients

Repetitive transcranial magnetic stimulation (rTMS) has been successfully used to help patients with treatment resistant depression. However, its role in alleviating self injuries...

Sponsor: Central South UniversityEnrolling: 601 location