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ANCA Associated Vasculitis (AAV) Clinical Trials

11 recruiting trials for ANCA Associated Vasculitis (AAV). Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
11
Total Trials
11
Recruiting Now
1
Phase 3 Trials
10
Sponsors

Recruiting Trials

RECRUITINGNCT06642870

Rare AutoImmune SElf-management Programme Development

The rare autoimmune rheumatic diseases (RAIRDs) are life-long multi-system diseases that are life or organ threatening. RAIRDs can impair quality of life similar to chronic...

Sponsor: University of the West of EnglandEnrolling: 3601 location
RECRUITINGNCT07150000

Clinical Assessment for Rheumatologic Disease - Research and Advancement in Safety and Efficacy

The CARe RAiSE project represents a pioneering translational initiative aimed at advancing precision medicine in the treatment of autoimmune rheumatic diseases. The primary...

Sponsor: University of BonnEnrolling: 1201 location
RECRUITINGPhase 1NCT06980597

A Study of OL-108 in Relapsed/Refractory Autoimmune Diseases

This study aims to characterize the safety, tolerability, pharmacokinetics, and preliminary efficacy of OL-108 in relapsed/refractory autoimmune diseases.

Sponsor: Beijing GoBroad HospitalEnrolling: 442 locations
RECRUITINGPhase 1 / Phase 2NCT06828042

Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refractory Autoimmune Diseases

Autoimmune diseases refer to a common category of diseases caused by the immune system reacting to self-antigens, leading to tissue damage. Autoimmune diseases encompass a wide...

Sponsor: Peking University Third HospitalEnrolling: 91 location
RECRUITINGNCT06614270

Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases

This study is a single-center, open-label, single-arm, dose-escalation trial. The aim of this study is to investigate the safety and efficacy of Anti-CD19 IL-10/IL15 CAR-NK cells...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 151 location
RECRUITINGPhase 1NCT06941129

CAR T-cell Therapy Targeting CD19 and BCMA in Patients With Relapse/Refractory Autoimmune Diseases

CAR T-cell Therapy Targeting CD19 and BCMA in Patients With Relapse/Refractory Autoimmune Diseases

Sponsor: Institute of Hematology & Blood Diseases Hospital, ChinaEnrolling: 121 location
RECRUITINGPhase 1 / Phase 2NCT07089121

Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders

Safety, tolerability and efficacy of Descarte-08 in children, adolescents and young adults with childhood-onset systemic lupus erythematosus, ANCA-associated vasculitis, juvenile...

Sponsor: Cartesian TherapeuticsEnrolling: 502 locations
RECRUITINGPhase 3NCT07168161

BDB-001 Phase III Trial in ANCA-Associated Vasculitis

The primary aim is to study the efficacy of treatment with BDB-001 Injection to induce remission in patients with active anti-neutrophil cytoplasmic antibody (ANCA)-associated...

Sponsor: Staidson (Beijing) Biopharmaceuticals Co., LtdEnrolling: 30020 locations
RECRUITINGPhase 2NCT06868290

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Severe Active GPA or MPA

The purpose of this study is to evaluate the efficacy and safety of rapcabtagene autoleucel versus comparator in participants with severe active Granulomatosis with Polyangiitis...

Sponsor: Novartis PharmaceuticalsEnrolling: 12620 locations
RECRUITINGPhase 4NCT06611696

Avacopan vs Reduced-dose Glucocorticoids in ANCA-associated Vasculitis

The goal of this clinical trial is to learn if avacopan in combination with short-term (4 weeks) reduced-dose glucocorticoid and rituximab works to treat patients with newly-onset...

Sponsor: Chiba UniversityEnrolling: 16020 locations
RECRUITINGNCT06696027

AYLo - AutoimmunitY and Loss of y

The AYLo study (AutoimmunitY and Loss of y - Investigating the Role of Hematopoietic Mutations and Mosaic Mutation in the Y Chromosome in Autoimmune Rheumatologic Diseases) aims...

Sponsor: University of BonnEnrolling: 5001 location