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Second Affiliated Hospital, School of Medicine, Zhejiang University

25 clinical trials · 25 recruiting · OTHER

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by Second Affiliated Hospital, School of Medicine, Zhejiang University

RECRUITINGNCT04960839

Prophylactic Irradiation to the Contralateral Breast for BCAs Patients

Breast cancer is the most common cancer in women worldwide, with high mortality. About 5% to 10% of breast cancers are hereditary. Most inherited cases of breast cancer are...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 3238 locations
Breast Cancer
RECRUITINGPhase 2NCT06554600

A Study of Zanubrutinib in Combination With Polatuzumab Vedotin, Bendamustine and Rituximab in the Treatment of...

This is a prospective, multicenter, single-arm, open phase II study to explore the efficacy and safety of Zanubrutinib in combination with Polatuzumab Vedotin, bendamustine, and...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 361 location
Refractory or Relapsed Diffuse Large B Cell Lymphoma
RECRUITINGNCT07460037

Chinese-Specific Speech Imagery Coding Using High-Density ECoG

The goal of this study is to investigate whether high-density electrocorticography (ECoG) signals recorded from the surface of the brain can be used to decode neural...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 501 location
AphasiaDysarthriaALS+5
RECRUITINGPhase 2NCT06376292

A Prospective Single Arm Phase II Exploratory Study on the Combination of Whole Brain Radiotherapy, Thiotepa...

The goal of this prospective, single-arm exploratory clinical study is to explore the safty and efficacy of whole-brain radiotherapy combined with Thiotepa intrathecal injection...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 581 location
Solid Tumor Leptomeningeal Metastasis
RECRUITINGNCT06760221

Safety and Efficacy of Preoperative SBRT and Radical Surgery for Soft Tissue Sarcoma of Extremities

Currently, the effectiveness and safety of preoperative hypo-fractionated radiotherapy in treating extremity soft tissue sarcomas remain inconclusive, warranting further...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 201 location
Soft Tissue SarcomaStereotactic Body RadiotherapySurgery
RECRUITINGPhase 3NCT05484349

TIzanidine for the Preventive Treatment of Episodic MigrainE (TIME)

In this study,189 adult migraine patients aged 18-65 years (diagnosed with migraine without aura and/or migraine with aura, with at least a 1-year history)will be collected to...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1896 locations
Migraine Without AuraMigraine With Aura
RECRUITINGNCT07205263

RAINBOW-ICH Trial of AI Guided Minimally Invasive Neurosurgery for ICH

Intracerebral hemorrhage (ICH) is one of the most devastating forms of stroke, with high rates of death and disability worldwide. Despite advances in medical and surgical care,...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 10001 location
Basal Ganglia HemorrhageIntraventricular HemorrhageBrainstem Stroke+1
RECRUITINGPhase 3NCT06863571

Reduction of Edema With a Specialized Cocktail for Ultra-early Management in Ischemic Stroke

Large ischemic stroke is a severe subtype of acute ischemic stroke (AIS), often leading to malignant cerebral edema, elevated intracranial pressure, and poor functional outcomes....

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 681 location
Ischemic Stroke
RECRUITINGNCT06816199

The Safety and the Efficiency of Hyperbaric Oxygen in Traumatic Brain Injury

The goal of this observational study is to learn about the safety and long-term effects of hyperbaric oxygen therapy in participants over the age of 18 with traumatic brain injury...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 3001 location
Traumatic Brain Injury
RECRUITINGNCT06218485

FFR Versus IVUS with Angiography-Derived FFR for Clinical Outcomes in Patients with Coronary Artery Disease

To compare the clinical outcomes of fractional flow reserve (FFR)-guided strategy versus intravascular ultrasound (IVUS)-guided stent implantation after angiography-derived...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 194220 locations
Coronary Artery Disease
RECRUITINGPhase 4NCT04935021

Clinical Study of ATTR-CM

In this study, patients with ATTR-CM or gene carriers were selected to study the diagnosis and treatment, and long-term follow-up was conducted.

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1001 location
Transthyroxine Amyloidosis Cardiomyopathy
RECRUITINGNCT07263204

AI-Enabled Diagnosis and Prognosis of Hypertrophic Cardiomyopathy

By harnessing artificial intelligence to decode the 12-lead electrocardiogram, the project will enable precise ECG-based phenotyping of hypertrophic cardiomyopathy-accurately...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 150001 location
Hypertrophic Cardiomyopathy (HCM)Left Ventricular Hypertrophy
RECRUITINGPhase 4NCT02803294

Transcatheter Aortic Valve Replacement Single Center Registry in Chinese Population

The purpose of this study is to evaluate the safety and effectiveness of transcatheter aortic valve replacement in Chinese population.

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 20001 location
Symptomatic Aortic Stenosis
RECRUITINGNCT05511792

Down Sizing Strategy (HANGZHOU Solution) vs Standard Sizing Strategy TAVR in Bicuspid Aortic Stenosis (Type 0)

To compare down sizing strategy versus annular sizing strategy technique (control group) in Type 0 bicuspid aortic stenosis (AS) patients undergoing transcatheter aortic valve...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 20615 locations
Aortic Stenosis With Bicuspid Valve
RECRUITINGNCT04454177

SMART Watch Facilitated Early Discharge in Patients Undergoing Transcatheter Aortic Valve Replacement

The purpose of this study is to observe conduction disturbance, daily activity level, heart rates, oxygen saturation in patients who underwent Transcatheter Aortic Valve...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1001 location
Aortic StenosisValvular Heart DiseaseTranscatheter Aortic Valve Replacement
RECRUITINGPhase 3NCT04067505

Rivaroxaban for the Prevention of Deep Vein Thrombosis in Patients With Left Iliac Vein Compression - The PLICTS Study

The purpose of this study is to evaluate the efficacy and safety of rivaroxaban for the prevention of deep vein thrombosis in patients with left iliac vein compression treated...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 2249 locations
May-Thurner Syndrome
RECRUITINGNCT05502965

Specific Dietary Pattern for Crohn's Disease Patients Following Surgery

Over the past 10 years, there are a large number of dietary treatments related to the CD, such as specific carbohydrate diet, low Fermentable Oligo-, Di-, Mono-saccharides And...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 351 location
Crohn Disease
RECRUITINGNCT07444060

Guselkumab Vs Ustekinumab in Stricturing Crohn's Disease

This study intends to select patients with confirmed moderate-to-severe Crohn's disease (CD) and obstructive symptoms of intestinal stenosis, who have clear evidence of lumen...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1001 location
CD - Crohn's DiseaseStricture; BowelIBD - Inflammatory Bowel Disease
RECRUITINGNCT06614270

Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases

This study is a single-center, open-label, single-arm, dose-escalation trial. The aim of this study is to investigate the safety and efficacy of Anti-CD19 IL-10/IL15 CAR-NK cells...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 151 location
Systemic Sclerosis (SSc)ANCA Associated Vasculitis (AAV)Idiopathic Inflammatory Myopathy (IIM)+3
RECRUITINGPhase 4NCT07114120

Clinical Study on the Treatment of Stable Bronchiectasis With Bailing Capsules Combined With Guben Kechuan Granules

The goal of this clinical trial is to learn if Bailing Capsules in combination Guben Kechuan Granules works to treat stable bronchiectasis in adults.It will also learn about the...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 2145 locations
BronchiectasisCOPD
RECRUITINGNCT04966793

Microbial Colonization Distribution and Adaptive Evolution of Lower Respiratory Tract in Bronchiectasis Patients.

Qualified sputum samples from bronchiectasis patients were collected regularly every month for three consecutive years to analyze the microbiome changes of lower respiratory tract...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 18501 location
Bronchiectasis
RECRUITINGNCT07354009

Efficacy and Safety of iStent in Reducing Intraocular Pressure in Open-angle Glaucoma

To evaluate the efficacy and safety of istent inject W in reducing intraocular pressure in Chinese adult patients with open-angle glaucoma complicated with cataract.

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 601 location
Glaucoma
RECRUITINGNCT07002372

Effect of Video Viewing on Intravitreal Injection Experience

Study Objective The goal of this clinical trial is to evaluate whether viewing a procedural video can improve the patient experience and reduce the incidence and severity of...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1821 location
Age Related Macular DegenerationDiabetic RetinopathyChoroidal Neovascularization+2
RECRUITINGNCT04833491

Study of the Correlation Between Preoperative Precise Biometrics, Spatial Assessment and Postoperative Visual Quality...

This study summarizes the experience of precision treatment and postoperative management of various types of cataract, and intend to further improve the quality of Clinical...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 10001 location
Recruitment of Participants
RECRUITINGPhase 1NCT06754358

Clinical Application Comparison of Two Femtosecond Laser Systems

The goal of this clinical trial is to compare the perioperative parameters of femtosecond laser-assisted cataract surgery (FLACS) using two laser systems. Participants will:...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1001 location
Cataract