A Study to See How RO7763505 Works and How Safe it is When Given to Healthy People and People With Stable Heart Disease
A Phase I, Randomized, Double-Blind, Adaptive, Placebo-Controlled, Single- Ascending Dose and Multiple-Ascending Dose, Parallel Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of RO7763505 Following Oral Administration in Healthy Participants and Patients With Stable Coronary Artery Disease
About This Trial
This study will evaluate safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending doses (SAD) (Part 1a), multiple ascending doses (MAD) (Part 1b), and the food effect (Part 1c) of RO7763505 in healthy adult participant. In Part 2, the safety, tolerability, PK and PD of multiple doses of RO7763505 in participants with stable coronary artery diseases (CAD).
Who May Be Eligible (Plain English)
Original Eligibility Criteria
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Treatments Being Tested
RO7763505
Participants will receive RO7763505 as per the schedule described in the protocol.
Placebo
Participants will receive matching placebo as per the schedule described in the protocol.