Skip to main content
TrialFinder
TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor about whether a trial is right for you.
RECRUITINGINTERVENTIONAL

Siemens Biomarker Multi-modality

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The purpose of this study is to see how well Photon Counting CT (PCCT) and ultrasound test results can find fat and scarring in the liver. They will be compared to MRI test results as the reference standard. Participants will get a regular CT scan on the PCCT scanner, plus a few extra pictures just for the study. They will also get an MRI, either on the same day or a different day, whichever is preferred. Participants will get an ultrasound on the same day as the MRI. If they have not had a hematocrit blood test in the past 24 hours, they will also receive one on the day of the CT scan.

Who May Be Eligible (Plain English)

Who May Qualify: - Age of 18 years or older - Has clinically indicated CT schedule including the liver (with contrast or with and without contrast) - Patient eligible for MR imaging - History of chronic diffuse liver disease, steatotic liver disease, and/ or liver fibrosis - Capable of consent Who Should NOT Join This Trial: - Contraindications to any of the required imaging examinations - BMI \> 45 (based on MRI scanner capacity) Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Age of 18 years or older * Has clinically indicated CT schedule including the liver (with contrast or with and without contrast) * Patient eligible for MR imaging * History of chronic diffuse liver disease, steatotic liver disease, and/ or liver fibrosis * Capable of consent Exclusion Criteria: * Contraindications to any of the required imaging examinations * BMI \> 45 (based on MRI scanner capacity)

Treatments Being Tested

DIAGNOSTIC_TEST

Photon-counting CT (PCCT)

Photon-counting computed tomography (PCCT) is a next-generation imaging technology using advanced detectors that directly count individual X-ray photons and measure their energy, rather than integrating total energy like traditional CT.

DIAGNOSTIC_TEST

Ultrasound

Ultrasound is a safe, radiation-free imaging technique using high-frequency sound waves to visualize soft tissues, organs, and blood flow in real-time.

DIAGNOSTIC_TEST

Magnetic Resonance Imaging (MRI)

MRI is a noninvasive, radiation-free medical imaging technique that uses powerful magnets and radio waves to generate detailed, high-resolution 3D images of soft tissues, organs, and bones.

Locations (1)

Duke University Medical Center
Durham, North Carolina, United States