RECRUITINGINTERVENTIONAL

Nutritional Intervention for College Students With Depression

About This Trial

The goal of this clinical trial is to assess the feasibility of nutritional interventions in college students with depression. The main outcomes it aims to measure are: * Nutritional content, meal timing, and sleep patterns in college students with depression * Feasibility of nutritional interventions (Mediterranean Diet and Time-Restricted Eating + Mediterranean Diet) in college students with depression Researchers will compare two groups - Mediterranean Diet (Med-Diet) and Time-Restricted Eating + Mediterranean Diet (TRE + Med-Diet) - to assess adherence to the dietary interventions and overall feasibility of the study procedures. Participants will: * Complete a 2-week baseline logging diet, sleep, activity, and mood * Be randomized to Mediterranean Diet (Med-Diet) or Time-Restricted Eating + Med-Diet (TRE + Med-Diet) * Participate in dietary counseling with a registered dietitian during the 8-week intervention * Continue to log diet, wear an actigraphy device, and complete mood, sleep, and diet assessments throughout the intervention

Who May Be Eligible (Plain English)

Who May Qualify: - Age ≥ 18 years and enrolled as a college student - Symptoms of mild to moderate depression - Receiving treatment for depression or willing to receive treatment during study participation - Generally in good physical health - On a stable dose of any medication affecting weight, metabolism, or mental health Who Should NOT Join This Trial: - Elevated risk for suicide - Inability to participate safely, as determined by the study physician - Lifetime diagnosis of bipolar disorder, schizophrenia, or post-traumatic stress disorder - Current eating disorder (e.g., bulimia, anorexia nervosa, binge eating) - Current alcohol or substance use disorder - Shift work outside of class schedule in the past 30 days - Pregnancy or lactation - Treatment with an investigational drug for depression or participation in another study requiring modification of diet Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Inclusion Criteria: * Age ≥ 18 years and enrolled as a college student * Symptoms of mild to moderate depression * Receiving treatment for depression or willing to receive treatment during study participation * Generally in good physical health * On a stable dose of any medication affecting weight, metabolism, or mental health Exclusion Criteria: * Elevated risk for suicide * Inability to participate safely, as determined by the study physician * Lifetime diagnosis of bipolar disorder, schizophrenia, or post-traumatic stress disorder * Current eating disorder (e.g., bulimia, anorexia nervosa, binge eating) * Current alcohol or substance use disorder * Shift work outside of class schedule in the past 30 days * Pregnancy or lactation * Treatment with an investigational drug for depression or participation in another study requiring modification of diet

Treatments Being Tested

BEHAVIORAL

Mediterranean Diet

Participants will receive ongoing dietary counseling, nutritional resources, and practical tips to support adoption of a Mediterranean-style dietary pattern emphasizing healthy fats (e.g., olive oil), whole grains, fruits, vegetables, and legumes, while limiting red meat and dairy products throughout the intervention period.

BEHAVIORAL

Time-Restricted Eating

Participants will receive guidance to restrict daily food intake to a consistent 10-hour eating window.

Locations (1)

University of California San Diego

La Jolla, California, United States