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RECRUITINGINTERVENTIONAL

Laparoscopic Versus Open Nephrectomy : Clinical Effectivness and Cost Analysis

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

To evaluate and compare clinical effectiveness (operative time, blood loss, hospital stay, complications and etc) and cost analysis' between laparoscopic nephrectomy and open nephrectomy .

Who May Be Eligible (Plain English)

Who May Qualify: - American Society of Anesthesiology score 1-3. - Indication for : - Simple total nephrectomy or hemi nephrectomy: benign chronic inflammatory non-functioning kidney - Partial nephrectomy: localized renal mass ≤7 cm suitable for nephron-sparing surgery. - Radical nephrectomy or Radical nephrouretrectomy with bladder cuff: localized renal tumor requiring complete nephrectomy without major vascular invasion. - Patient deemed fit for general anesthesia and surgery. - Patient provides written willing to sign a consent form. Who Should NOT Join This Trial: - emergency surgery, dialysis-dependent patients, planned hybrid procedures. - Patients with incomplete data - Patients with metastatic disease at presentation. - Prior extensive ipsilateral retroperitoneal surgery or severe adhesions precluding Laparoscopy. - Need for concomitant major procedures (eg, large bowel resection) at index operation. - Locally advanced tumor with obvious major vascular involvement requiring complex vascular reconstruction. - Uncorrected coagulopathy. - Pregnancy or Obese patient (BMI \> 40) - Inability to provide willing to sign a consent form or comply with follow-up. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * American Society of Anesthesiology score 1-3. * Indication for : * Simple total nephrectomy or hemi nephrectomy: benign chronic inflammatory non-functioning kidney * Partial nephrectomy: localized renal mass ≤7 cm suitable for nephron-sparing surgery. * Radical nephrectomy or Radical nephrouretrectomy with bladder cuff: localized renal tumor requiring complete nephrectomy without major vascular invasion. * Patient deemed fit for general anesthesia and surgery. * Patient provides written informed consent. Exclusion Criteria: * emergency surgery, dialysis-dependent patients, planned hybrid procedures. * Patients with incomplete data * Patients with metastatic disease at presentation. * Prior extensive ipsilateral retroperitoneal surgery or severe adhesions precluding Laparoscopy. * Need for concomitant major procedures (eg, large bowel resection) at index operation. * Locally advanced tumor with obvious major vascular involvement requiring complex vascular reconstruction. * Uncorrected coagulopathy. * Pregnancy or Obese patient (BMI \> 40) * Inability to provide informed consent or comply with follow-up.

Treatments Being Tested

PROCEDURE

open or laparoscopic nephrectomy

compare post operative recovery , estimated blood loss and cost analysis between open and laparosopic nephrectomy.

Locations (1)

Menoufia Faculty of Medicine
Shibīn al Kawm, Shebin Elkom, Egypt