RECRUITINGOBSERVATIONAL

Heart Failure With Preserved Ejection Fraction in Patients With Сhronic Obstructive Pulmonary Disease: Clinical Course and Prognosis

About This Trial

Study aim is comparison of heart failire with preserved ejection fraction (HFpEF) detection rate in patients with Сhronic Obstructive Pulmonary Disease (COPD) and the clinical course and prognosis in patients with COPD depending on HFpEF presence.

Who May Be Eligible (Plain English)

Who May Qualify: 1. Verified diagnosis of COPD; 2. Patients hospitalized with COPD; 3. Citizenship of the Russian Federation; 4. Patients aged 50 to 70 years; 5. Patient consent to participate in the study. Who Should NOT Join This Trial: 1. Lack of Russian Federaion citizenship; 2. Patient's refusal to participate in the study; 3. Any chronic diseases, other than COPD, that affect the prognosis, in the acute and/or decompensated stage; 4. Mental disorders. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Inclusion Criteria: 1. Verified diagnosis of COPD; 2. Patients hospitalized with COPD; 3. Citizenship of the Russian Federation; 4. Patients aged 50 to 70 years; 5. Patient consent to participate in the study. Exclusion Criteria: 1. Lack of Russian Federaion citizenship; 2. Patient's refusal to participate in the study; 3. Any chronic diseases, other than COPD, that affect the prognosis, in the acute and/or decompensated stage; 4. Mental disorders.

Treatments Being Tested

DIAGNOSTIC_TEST

Echocardiography

Transthoracic echocardiography at rest: with determination of epicardial fat tissue thickness, epicardial adipose tissue thickness (EAT), E/e', interventricular septum thickness, left ventricular posterior wall thickness, and end-diastolic dimension

DIAGNOSTIC_TEST

Spirometry

Spirometry is the most common of the pulmonary function tests, which measures the lung capacity and airway patency (volume and speed of air) during quiet and forced breathing.

DIAGNOSTIC_TEST

Body plethysmography

Body plethysmography is a non-invasive lung function test performed in a sealed booth (body box) that measures total lung volume, functional residual capacity, and airway resistance by using Boyle's Law to track pressure and volume changes as a patient breathes, providing crucial data for diagnosing conditions like COPD and asthma, and differentiating them from other lung disorders

DIAGNOSTIC_TEST

6-Minute Walk Test (6MWT)

The 6 Minute Walk Test is a sub-maximal exercise test used to assess aerobic capacity and endurance. The distance covered over a time of 6 minutes is used as the outcome by which to compare changes in performance capacity

DIAGNOSTIC_TEST

laboratory biomarker analysis

Routine and special laboratory tests

Locations (2)

Kazan State Medical University

Kazan', Russia

National Medical Research Center for Therapy and Preventive Medicine

Moscow, Russia