RECRUITINGOBSERVATIONAL
Multimodal Analysis of Endomyocardial Biopsies
About This Trial
The goal of this observational study is to pursue a multimodal approach to identify the molecular signatures and immune signalling molecules of various myocardial diseases and thereby contribute to improving diagnosis and therapy. The main aim is: -Identification of molecular profiles (e.g., proteome, lipidome, metabolome) and immune signalling profiles that are specifically associated with different myocardial diseases and the post-heart transplantation course. Participants already receiving an endomyocardial biopsy as part of their regular medical care will be enrolled. An additional biopsy sample will be taken for the above mentioned research.
Who May Be Eligible (Plain English)
Who May Qualify:
- Patients aged \>18 years with a clinical indication for endomyocardial biopsy.
- Patients capable of providing willing to sign a consent form who have signed the consent form for participation in the study.
Who Should NOT Join This Trial:
- Patients without a clinical indication for endomyocardial biopsy (EMB).
- Pregnant individuals.
- Patients incapable of providing willing to sign a consent form.
- Women of childbearing potential who are not using adequate contraception.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Patients aged \>18 years with a clinical indication for endomyocardial biopsy.
* Patients capable of providing informed consent who have signed the consent form for participation in the study.
Exclusion Criteria:
* Patients without a clinical indication for endomyocardial biopsy (EMB).
* Pregnant individuals.
* Patients incapable of providing informed consent.
* Women of childbearing potential who are not using adequate contraception.
Locations (1)
Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen, University Hospital Essen, Germany
Essen, North Rhine-Westphalia, Germany