RECRUITINGOBSERVATIONAL
Impact of the New Generation Anti-diabetic Drugs on Diabetic Retinopathy
About This Trial
This study aims to test the impact of new-generation anti-diabetic drugs, such as SGLT2 inhibitors and DPP-4 inhibitors, on the development of diabetic retinopathy (DR). The study hypothesizes that these drugs have protective effects in diabetic retinopathy by delaying its incidence compared to older agents (including metformin) only. Early intervention is critical, as treatment options for advanced stages of DR are limited in terms of their ability to restore impaired vision and their high associated costs. By focusing on delaying the occurrence of diabetic retinopathy, the investigators aim to reduce the burden of DR and improve the quality of life for diabetic patients.
Who May Be Eligible (Plain English)
Who May Qualify:
- Diagnosed with Type 2 Diabetes for \>5 years
- Using Diabetes medications (metformin, sulfonylureas, SGLT2 inhibitors, DPP-4 inhibitors) for a period of 2-3 years
Who Should NOT Join This Trial:
- Gestational Diabetes
- Type 1 Diabetes
- Severe non-proliferative diabetic retinopathy (NPDR) at baseline
- Proliferative diabetic retinopathy (PDR) at baseline
- Pregnant and breastfeeding women
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Diagnosed with Type 2 Diabetes for \>5 years
* Using Diabetes medications (metformin, sulfonylureas, SGLT2 inhibitors, DPP-4 inhibitors) for a period of 2-3 years
Exclusion Criteria:
* Gestational Diabetes
* Type 1 Diabetes
* Severe non-proliferative diabetic retinopathy (NPDR) at baseline
* Proliferative diabetic retinopathy (PDR) at baseline
* Pregnant and breastfeeding women
Locations (1)
Alexandria University Main Hospitals - Diabetes clinics/ Ophthalmology clinics
Alexandria, Egypt