IMT in Asthma: Activity, Coping, Self-Management

Who May Qualify: - Being between the ages of 18-65 - Having been diagnosed with severe persistent, non-allergic asthma by a pulmonologist in accordance with the Global Initiative for Asthma (GINA) guideline criteria, - Patients with type 2 inflammation markers. According to accepted standards; peripheral eosinophils \<150/µL and/or negative skin prick test and/or total IgE \<30 kU/L - Bronchodilator response (\>12% or 200 mL improvement in FEV1% predicted following inhalation of 400 mg salbutamol) - Diagnosis-follow-up period: Patients diagnosed at least 6 months prior, under follow-up and treatment, and/or with controlled asthma - Having completed the pulmonary rehabilitation program - Completion of 8 weeks of inspiratory muscle training (IMT) - Patients who have read, understood, and signed the willing to sign a consent form form Who Should NOT Join This Trial: - Having recently had a respiratory tract infection recently (within the last month), - Having a smoking history of more than 10 pack-years or having a history of smoking within 6 months after quitting smoking - Having received oral corticosteroid treatment in the last 4 weeks, - Having a Body Mass Index \>35, - Eosinophilic Granulomatosis Polyangiitis (EGPA) and Allergic Bronchopulmonary Aspergillosis (ABPA), - Vasculitis, - History of malignancy, - Pregnancy, - Previous lung surgery, use of long-term oxygen therapy - Having accompanying restrictive lung diseases (advanced kyphoscoliosis, ankylosing spondylitis) and neuromuscular diseases (myastania gravis, muscular dystrophies, myopathies) that will prevent healthy respiratory function testing and rehabilitation. - Cognitive dysfunction, mental retardation, dementia, or other conditions that make it difficult to follow the protocol, - Unwillingness to continue participating in the study, - Communication difficulties or intellectual deficiencies Always talk to your doctor about whether this trial is right for you.