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RECRUITINGINTERVENTIONAL

Impact of Pre-Ablation Prehabilitation on Clinical Outcomes and Cardiorespiratory Fitness in Atrial Fibrillation Patients

Impact of Pre-Ablation Prehabilitation on Clinical Outcomes and Cardiorespiratory Fitness in Patients With Atrial Fibrillation: A Randomized Controlled Trial

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The primary objective of this study is to compare the effects of a preoperative prehabilitation program versus usual care on post-procedural cardiorespiratory function and clinical outcomes in patients undergoing catheter ablation for atrial fibrillation.

Who May Be Eligible (Plain English)

Who May Qualify: 1. Aged 18-70 years 2. Scheduled for first AF ablation 3. NYHA class I-II 4. LVEF ≥ 50% Who Should NOT Join This Trial: 1. Significant structural heart disease (e.g., severe valvular disease) 2. Contraindications to CPET or exercise training 3. Cognitive impairment preventing cooperation Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: 1. Aged 18-70 years 2. Scheduled for first AF ablation 3. NYHA class I-II 4. LVEF ≥ 50% Exclusion Criteria: 1. Significant structural heart disease (e.g., severe valvular disease) 2. Contraindications to CPET or exercise training 3. Cognitive impairment preventing cooperation

Treatments Being Tested

OTHER

4-week structured prehabilitation program (exercise training + psychological education)

The prehabilitation group will receive a 4-week structured program before ablation, including: Individualized exercise training: Prescription based on cardiopulmonary exercise test results, including aerobic exercise (40%-60% of heart rate reserve) and resistance training Psychological and educational intervention: Structured education based on cognitive behavioral therapy principles, focusing on addressing kinesiophobia Delivery mode: Hybrid (supervised in-hospital sessions + monitored home-based sessions) The usual care group will receive only standard preoperative education without structured rehabilitation.

Locations (1)

The First Affiliated Hospital with Nanjing Medical University
Nanjing, Please Select, China