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RECRUITINGOBSERVATIONAL

Real-World Study on Fecal Microbiota Transplantation: Long-Term Effectiveness and Safety Statistics

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This is a large-scale observational study aiming to evaluate the long-term effectiveness and safety of Fecal Microbiota Transplantation (FMT). FMT is a procedure that transfers gut bacteria from healthy donors to patients to restore a balanced gut microbiome. The study will follow approximately 4,000 patients who have received or will receive FMT for conditions like recurrent C. difficile infection, inflammatory bowel disease, functional gastrointestinal disorders, and certain neurological conditions. The main goals are to: * Assess the disease remission rates at 3 months, 1 year, and 5 years after FMT. * Monitor the long-term safety and any potential side effects. * Identify factors that may influence how well a patient responds to the treatment. This research will use both existing patient data (retrospective cohort) and newly collected data from future patients (prospective cohort). The findings are expected to help improve and standardize FMT treatment for better patient care.

Who May Be Eligible (Plain English)

Who May Qualify: - Diagnosed with one of the target diseases. - Age ≥ 3 years. - Have received at least one Fecal Microbiota Transplantation (FMT) treatment. - Availability of complete baseline and follow-up data for analysis. - Provide signed willing to sign a consent form (for the prospective cohort) OR consent for the use of clinical data (for the retrospective cohort). Who Should NOT Join This Trial: - Clinical data is severely missing, making efficacy assessment impossible. - Presence of severe complications that may jeopardize safety or confound the study results. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Diagnosed with one of the target diseases. * Age ≥ 3 years. * Have received at least one Fecal Microbiota Transplantation (FMT) treatment. * Availability of complete baseline and follow-up data for analysis. * Provide signed informed consent (for the prospective cohort) OR consent for the use of clinical data (for the retrospective cohort). Exclusion Criteria: * Clinical data is severely missing, making efficacy assessment impossible. * Presence of severe complications that may jeopardize safety or confound the study results.

Locations (1)

Shanghai Tenth People's Hospital
Shanghai, Shanghai Municipality, China