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RECRUITINGINTERVENTIONAL

Effect of Omega-3 Fatty Acids on Eye Blood Vessels in Type 1 Diabetes

Role of Omega-3 Fatty Acids in Modulating Retinal Microvascular Changes in Type 1 Diabetes

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The aim of this clinical trial is to learn if omega-3 fatty acid supplements help maintain healthy blood vessels in the eyes of adults with type 1 diabetes. It will also learn about the safety of omega-3 supplements. The main questions it aims to answer are: Do omega-3 supplements improve the health of retinal blood vessels in adults with type 1 diabetes? Are there any side effects when taking omega-3 supplements? Researchers will compare participants taking omega-3 supplements to a control group (if applicable) to see if the supplements help support retinal blood vessel health. Participants will: Take a daily omega-3 supplement for the duration of the study Attend regular eye exams to monitor changes in the retina Report any side effects or health changes during the study

Who May Be Eligible (Plain English)

Who May Qualify: Diagnosis of Type 1 Diabetes Age between 10 and 45 years Duration of diabetes ≥ 2 years Mild to moderate diabetic retinopathy allowed (based on fundus examination) Who Should NOT Join This Trial: Presence of any ocular disease other than diabetic retinopathy Use of medications that may affect retinal vascular measurements or visual function outcomes Presence of systemic diseases other than diabetes (e.g., uncontrolled hypertension, autoimmune conditions (where your immune system attacks your own body)s) History of ocular surgery within the past 6 months Current participation in another interventional clinical trial Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: Diagnosis of Type 1 Diabetes Age between 10 and 45 years Duration of diabetes ≥ 2 years Mild to moderate diabetic retinopathy allowed (based on fundus examination) Exclusion Criteria: Presence of any ocular disease other than diabetic retinopathy Use of medications that may affect retinal vascular measurements or visual function outcomes Presence of systemic diseases other than diabetes (e.g., uncontrolled hypertension, autoimmune diseases) History of ocular surgery within the past 6 months Current participation in another interventional clinical trial

Treatments Being Tested

DIETARY_SUPPLEMENT

Omega 3 Fish Oil supplements

Arm 1 - Omega-3 Supplement Group: Intervention Type: Dietary Supplement Intervention Name: Omega-3 Fatty Acid Supplement Intervention Description: Participants will take one daily capsule containing 1000 mg of combined EPA and DHA. The supplement is taken orally with food. Eye exams will be performed every three months to monitor retinal blood vessel health. Participants will report any side effects such as mild stomach upset. Arm 2 - Placebo / Control Group: Intervention Type: Placebo Intervention Name: Placebo Capsule Intervention Description: Participants will take a daily capsule that looks identical to the omega-3 supplement but contains no active omega-3 fatty acids. Eye exams will be performed every three months to monitor retinal blood vessel health. Participants will report any health changes.

Locations (1)

Children Hospital Lahore and Ali Fatima Hospital
Lahore, Punjab Province, Pakistan