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RECRUITINGOBSERVATIONAL

Performance of Large Language Models for Structured Recognition and Refractive Prediction

Head-to-Head Evaluation of ChatGPT 4o, GPT-5, and DeepSeek for Structured Extraction, Toric IOL Recommendation, and Refractive Prediction

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

We conducted a single-center, retrospective observational study to evaluate large language models (ChatGPT 4o, GPT-5, DeepSeek) for automated interpretation of de-identified IOLMaster 700 reports provided as raster images. Models produced structured biometric extraction, toric IOL recommendation, and refractive predictions (sphere, cylinder, axis). Primary outcomes included parameter-level agreement and refractive error metrics; secondary outcomes included decision-support performance for toric IOL selection and agreement on ordered T-codes. No clinical intervention was performed.

Who May Be Eligible (Plain English)

Who May Qualify: -postoperative corrected distance visual acuity (CDVA) of 0.10 logMAR or better -an absolute IOL rotational stability of less than 10∘ at the 1-month follow-up examination Who Should NOT Join This Trial: - incomplete biometric data on the examination report; - a history of previous ocular surgery or ocular trauma - the occurrence of intraoperative complications, such as an anterior capsular tear or posterior capsular rupture - the development of significant postoperative complications, including but not limited to severe intraocular infection or inadequate pupillary dilation. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: -postoperative corrected distance visual acuity (CDVA) of 0.10 logMAR or better -an absolute IOL rotational stability of less than 10∘ at the 1-month follow-up examination Exclusion Criteria: * incomplete biometric data on the examination report; * a history of previous ocular surgery or ocular trauma * the occurrence of intraoperative complications, such as an anterior capsular tear or posterior capsular rupture * the development of significant postoperative complications, including but not limited to severe intraocular infection or inadequate pupillary dilation.

Locations (1)

Eye and ENT hospital of Fudan University
Shanghai, Shanghai Municipality, China