Skip to main content
TrialFinder
TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor about whether a trial is right for you.
RECRUITINGOBSERVATIONAL

Cardiac Amyloid Deposits and Heart Dysfunction in Alzheimer's Disease

Investigation of Cardiac Amyloid Deposits as a Cause of Cardiac Dysfunction in Alzheimer's Disease (Untersuchung Von Kardialen Amyloidablagerungen Als Ursache Einer Funktionseinschränkung Des Herzens Bei Alzheimer Demenz)

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This study seeks to explore the possible common pathogenesis of both cardiac amyloidosis and Alzheimer's disease, which can both be associated with amyloid deposits. Using Positron Emission Tomography (PET) scans with amyloid tracers - a conventional tool for non-invasively imaging amyloid deposits in Alzheimer's disease - the research will extend this imaging methodology to the heart. The study will conduct additional PET/MRI scans of the heart in patients undergoing amyloid tracer PET scans for Alzheimer's evaluations. Each participant will also undergo an echocardiogram and a clinical examination of dementia. This could potentially enhance diagnostic practices in both cardiac amyloidosis and Alzheimer's disease.

Who May Be Eligible (Plain English)

Who May Qualify: - Patients undergoing cerebral amyloid PET examination for clinical indication to clarify Alzheimer's disease - No contraindications to undergo an MRI examination - No contraindications to undergo an Amyloid PET scan Who Should NOT Join This Trial: - Patients with vascular dementia and confirmed other causes of dementia (e.g. stroke, vitamin deficiency, thyroid insufficiency, toxic causes such as alcohol) - Patients with pronounced cardiac preconditions - Pregnant and breastfeeding women Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Patients undergoing cerebral amyloid PET examination for clinical indication to clarify Alzheimer's disease * No contraindications to undergo an MRI examination * No contraindications to undergo an Amyloid PET scan Exclusion Criteria: * Patients with vascular dementia and confirmed other causes of dementia (e.g. stroke, vitamin deficiency, thyroid insufficiency, toxic causes such as alcohol) * Patients with pronounced cardiac preconditions * Pregnant and breastfeeding women

Locations (1)

University Hospital Essen
Essen, North Rhine-Westphalia, Germany