MRD-positive AML Clinical Study
MRD-positive AML: a Prospective, Single-arm, Multicenter Platform Clinical Study
About This Trial
This clinical trial is a platform-type clinical study intended to investigate the efficacy and safety of MRD-positive acute myeloid leukemia patients after comprehensive treatment, which includes but is not limited to the following drugs and protocols: Chemotherapy, small molecule targeted drugs, demethylation drugs, liposome drugs and the combination of these drugs to form a combination of treatment regimen, the specific treatment regimen will be updated according to the results of this trial and the latest research progress at home and abroad.
Who May Be Eligible (Plain English)
Original Eligibility Criteria
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Treatments Being Tested
Ivosidenib
500mg d1-28
Gilteritinib
120mg d1-28
Venetoclax
400mg d1-21 ; 400mg d1-7;400mg d1-28; 600mg d1-21
Avapritinib
200mg d1-28.
Daunorubicin
45mg/m2/d d1-2;
Cytarabine
100mg/m2/d d1-5
Idarubicin
10mg/m2/d d1-2
MTZ
8mg/m2/d d1-2
HHT
2mg/m2/d d1-5
Azacitidine
75mgd/m2 d1-7.