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RECRUITINGINTERVENTIONAL

Evaluation of Decision-Making Fatigue After Traumatic Brain Injury

Evaluation of Decision-Making Fatigue After Traumatic Brain Injury (EDIFY)

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This is a preliminary, prospective, cohort study to investigate the feasibility of using the COGED and Restless Bandit tasks after a mild to moderate traumatic brain injury as well as in healthy controls.

Who May Be Eligible (Plain English)

Inclusion Criteria for TBI Participants: - Adults 18 years and older - Diagnosis of a mild to moderate TBI (GCS \> 8 on admission) - Able to perform a computerized assessment - Willing to attend all scheduled appointments - Able to undergo the willing to sign a consent form process Inclusion Criteria for Healthy Participants: - Adults 18 years and older - Able to perform a computerized assessment - Willing to attend all scheduled appointments - Able to undergo the willing to sign a consent form process Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria for TBI Participants: * Adults 18 years and older * Diagnosis of a mild to moderate TBI (GCS \> 8 on admission) * Able to perform a computerized assessment * Willing to attend all scheduled appointments * Able to undergo the informed consent process Inclusion Criteria for Healthy Participants: * Adults 18 years and older * Able to perform a computerized assessment * Willing to attend all scheduled appointments * Able to undergo the informed consent process

Treatments Being Tested

BEHAVIORAL

COGED

The COGED task consists of the classic N-back task of working memory-based decision making, followed by a valuation phase. The N-back phase of the task allows calculation of cognitive performance of a working memory task. During valuation, participants receive titrating offers of differing amounts of money to perform different difficulty levels of the N-back. The result is an effort discounting curve used to measure the individual effort cost. Effort discounting curves show the perceived cognitive effort required to complete each level of the task relative to another (typically the 1-back).

BEHAVIORAL

Restless Bandit

Participants are presented with three targets (decks of cards) on the screen, which they select with a mouse movement. Each of the three targets is associated with a hidden probability of reward, which drifts unpredictably and independently across trials. This encourages participants to "exploit" good options when they are available, but also occasionally to "explore "other targets, which could become better at any time. Eye Tracking is done at each visit while the participant completes the Restless Bandit tasks.

Locations (1)

University of Minnesota
Minneapolis, Minnesota, United States