Study Safety and Efficacy of Deep Brain Stimulation (DBS) and Cervical Deep Lymphoid-venous Anastomosis (LVA) in Alzheimer's Disease

Who May Qualify: - Meeting the diagnostic criteria for dementia formulated by the National Institute on Aging-Alzheimer's Association (NIA-AA). - Clinical Dementia Rating (CDR) score of 3 points. - Ability to ambulate independently or with the aid of a walker/cane. - Adequate visual and auditory capacity to cooperate with examinations and treatment. - Voluntary participation with written willing to sign a consent form provided by both the subject and their legal guardian. Who Should NOT Join This Trial: - Pre-existing abnormal brain structure (e.g., tumor, cerebral infarction, hydrocephalus, or intracranial hemorrhage). - Comorbidity with other neurological disorders such as multiple sclerosis, epilepsy, or Parkinson's disease. - Psychiatric disorders: e.g., anxiety, depression, other affective disorders, or drug-induced psychosis. - Severe internal diseases, currently using respiratory/cardiovascular/anticonvulsant/psychotropic drugs, or clinically significant gastrointestinal, renal, hepatic, respiratory, infectious, endocrine, or cardiovascular diseases, cancer, alcoholism, or substance addiction. - Severe auditory or visual impairment. - Clinical comorbidities with life expectancy \<2 years. - History of cranial surgery. - Contraindications to MRI or transcranial alternating current stimulation (tACS) (e.g., cardiac pacemaker, post-deep brain stimulation surgery). - Eczema or sensitive skin. - Familial Alzheimer's disease. - Other types of dementia: e.g., vascular dementia, Lewy body dementia, frontotemporal dementia, or infectious dementia; - Any other condition deemed by the investigator as unsuitable for the study Always talk to your doctor about whether this trial is right for you.