RECRUITINGINTERVENTIONAL
Effect OF Lactase Enzyme Supplements ON Intolerance IN Preterm Neonates
Effect OF Lactase Enzyme Supplements ON Protection Against Feeding Intolerance IN Preterm Neonates
About This Trial
This study aims to study the effect of lactase enzyme in preventing feeding intolerance in preterm neonates in neonatal intensive care unit at Alexandria University Children's Hospital.
Who May Be Eligible (Plain English)
Inclusion criteria will be as follows:
- Preterm neonates ≤ 32 weeks gestational age.
- Start feeding in the first 72 hours of life. 8. Exclusion criteria
Patients with any of the following will be excluded:
1. Parental consent lacking/refusal.
2. Obvious major congenital abnormalities.
3. Infants more than 72 hours of age at the time of randomization.
4. Delayed introduction of feeding (beyond three days of life).
5. Known galactosemia.
6. Severe IUGR. -
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion criteria will be as follows:
* Preterm neonates ≤ 32 weeks gestational age.
* Start feeding in the first 72 hours of life. 8. Exclusion criteria
Patients with any of the following will be excluded:
1. Parental consent lacking/refusal.
2. Obvious major congenital abnormalities.
3. Infants more than 72 hours of age at the time of randomization.
4. Delayed introduction of feeding (beyond three days of life).
5. Known galactosemia.
6. Severe IUGR. -
Treatments Being Tested
DRUG
lactase administration
1 drop for each 10 ml of formula milk for 14 days
OTHER
placebo
10 ml milk without lactase
Locations (1)
Marwa Mohamed Farag
Alexandria, Egypt