Skip to main content
TrialFinder
TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor about whether a trial is right for you.
RECRUITINGINTERVENTIONAL

Gauging Outcomes of Total Milk Ingestion on Lipid and gControl

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Atherosclerotic cardiovascular disease remains the leading cause of death for adults in the United States. The cardiovascular impact of milk consumption remains a matter of long-standing scientific debate. Current guidelines for Americans recommend three daily servings of fat-free or low-fat (1%) dairy over full-fat options due to concerns that saturated fat may increase cardiovascular risk. Yet, the literature does not consistently support non-fat dairy as superior to high-fat dairy for reducing cardiometabolic risk. Identifying the comparative health benefits of non-fat versus high-fat dairy milk would be immediately applicable to patients who seek cardiovascular care. In this randomized, case-crossover trial, the investigators seek to efficiently assess the association between high-fat versus non-fat dairy milk consumption and insulin resistance. Utilizing the Eureka Platform, participants will be randomized to limit their liquid milk consumption to whole milk followed by skim milk (or vice versa), measuring the effect of milk fat content on glycemic index and lipid profile.

Who May Be Eligible (Plain English)

Who May Qualify: - Are age ≥18 years - Have a smartphone - Are able to use the Eureka mobile application - Consume, on average, at least one cup of dairy milk daily, at least 5 days per week Who Should NOT Join This Trial: - Non-English speaker - Are lactose intolerant - History of myocardial infarction - History of type I or type II diabetes - Familial hypercholesterolemia - Plan to change treatment for cholesterol - Unable to read or sign to provide willing to sign a consent form Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Are age ≥18 years * Have a smartphone * Are able to use the Eureka mobile application * Consume, on average, at least one cup of dairy milk daily, at least 5 days per week Exclusion Criteria: * Non-English speaker * Are lactose intolerant * History of myocardial infarction * History of type I or type II diabetes * Familial hypercholesterolemia * Plan to change treatment for cholesterol * Unable to read or sign to provide informed consent

Treatments Being Tested

BEHAVIORAL

Whole Milk-Skim Milk

If randomized to the whole milk-skim milk treatment sequence, participants will be instructed to restrict their liquid milk consumption to only whole milk for the first 2 months and to only skim milk for the last 2 months of the enrollment period. Participants will receive weekly app and text-based message reminders of their randomization assignments.

BEHAVIORAL

Skim Milk-Whole Milk

If randomized to the skim milk-whole milk treatment sequence, participants will be instructed to restrict their liquid milk consumption to only skim milk for the first 2 months and to only whole milk for the last 2 months of the enrollment period. Participants will receive weekly app and text-based message reminders of their randomization assignments.

Locations (1)

UCSF Medical Center at Parnassus
San Francisco, California, United States