RECRUITINGOBSERVATIONAL

Sepsis and Myocarditis

Cardiac Manifestations of Sepsis and Its Association With Disease Outcome: A Prospective Cohort Study

About This Trial

This prospective cohort study aims to investigate the cardiac manifestations of sepsis and their influence on disease outcomes among adult patients at Jimma University Medical Center, Ethiopia, from May 2025 to May 2026. The research will include adults aged 18 and older with sepsis, categorizing them based on the presence or absence of cardiac involvement, which will be assessed through clinical symptoms, biomarkers, ECG, and echocardiographic findings. The study will evaluate the persistence of cardiac abnormalities, functional capacity, and survival over one year, utilizing structured data collection and advanced statistical methods, including survival analysis and regression techniques, to identify predictors of adverse outcomes.

Who May Be Eligible (Plain English)

Who May Qualify: - All adult patients aged 18 years and above diagnosed with sepsis admitted to Jimma University Medical Center during the study periods that are willing to participate and continue follow-up of their disease condition for at least one year. Who Should NOT Join This Trial: - Patients with any kind of pre-existing established cardiac disease prior to their sepsis diagnosis and those who are not willing to participate or not willing to have follow-up of their disease condition for at least one year. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Inclusion Criteria: * All adult patients aged 18 years and above diagnosed with sepsis admitted to Jimma University Medical Center during the study periods that are willing to participate and continue follow-up of their disease condition for at least one year. Exclusion Criteria: * Patients with any kind of pre-existing established cardiac disease prior to their sepsis diagnosis and those who are not willing to participate or not willing to have follow-up of their disease condition for at least one year.

Treatments Being Tested

OTHER

Standard treatment for sepsis of any focus

This group of patients will be treated for the sepsis of any focus as per standard.

OTHER

Treatment for the sepsis with standard management of cardiac failure

This group of patients will be treated for the sepsis and management of cardiac failure with additional supportive care cocktails based on the specific indication.

Locations (1)

Jimma University Hospital

Jimma, Oromiya, Ethiopia