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RECRUITINGINTERVENTIONAL

Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE）

Comparison of the Application Effects of Different Drainage Modes in the Perioperative Period of Minimally Invasive Three-Field Radical Esophagectomy for Esophageal Cancer

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This RCT compares three drainage approaches after minimally invasive esophagectomy (chest tube + thoracic mediastinal drainage tube, thoracic, and abdominal mediastinal drainage tube) to evaluate perioperative outcomes, addressing current evidence gaps in pain and complication profiles.

Who May Be Eligible (Plain English)

Who May Qualify: - Age ≥18 years - Pathologically confirmed esophageal cancer requiring three-incision esophagectomy (cervical, thoracic, and abdominal incisions) - ASA physical status class I-III Who Should NOT Join This Trial: - History of chronic pain or long-term use of analgesics prior to surgery - Severe cardiopulmonary dysfunction (e.g., FEV1 \<50%) - Coagulation disorders or patients undergoing reoperation - Intraoperative findings of extensive pleural adhesions, combined resection of adjacent organs, or other conditions deemed by the investigator to warrant exclusion Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Age ≥18 years * Pathologically confirmed esophageal cancer requiring three-incision esophagectomy (cervical, thoracic, and abdominal incisions) * ASA physical status class I-III Exclusion Criteria: * History of chronic pain or long-term use of analgesics prior to surgery * Severe cardiopulmonary dysfunction (e.g., FEV1 \<50%) * Coagulation disorders or patients undergoing reoperation * Intraoperative findings of extensive pleural adhesions, combined resection of adjacent organs, or other conditions deemed by the investigator to warrant exclusion

Treatments Being Tested

PROCEDURE

Chest mediastinal tube

Transthoracic mediastinal drainage was performed for postoperative management of the patient.

PROCEDURE

Abdominal mediastinal tube

Transperitoneal mediastinal drainage was performed for postoperative management of the patient.

PROCEDURE

Chest tube + chest mediastinal tube

Chest tube insertion combined with transthoracic mediastinal drainage was performed for postoperative management of the patient.

Locations (1)

Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China