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RECRUITINGINTERVENTIONAL

Evaluation of Aqueous Humor DEL-1 and IL-17 Levels in Diabetic Cataract Patients

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

By comparing DEL-1 and IL-17 levels in the aqueous humor of diabetic cataract patients with the aqueous humor of non-diabetic patients, we aim to understand the biochemical effects of diabetes-related inflammatory processes in the eye.

Who May Be Eligible (Plain English)

Who May Qualify: - Cataract diagnosed and surgery planned - Patients without any other ocular pathology other than cataract. - Type 2 DM for at least 5 years in the diabetic group Who Should NOT Join This Trial: - Patients with previous intraocular surgery - Those with inflammatory eye diseases (e.g. uveitis) - Those with autoimmune conditions (where your immune system attacks your own body)s or systemic inflammatory diseases - Those receiving local or systemic steroid therapy - Those with severe systemic disease (e.g. advanced renal failure, malignancy) Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Cataract diagnosed and surgery planned * Patients without any other ocular pathology other than cataract. * Type 2 DM for at least 5 years in the diabetic group Exclusion Criteria: * Patients with previous intraocular surgery * Those with inflammatory eye diseases (e.g. uveitis) * Those with autoimmune diseases or systemic inflammatory diseases * Those receiving local or systemic steroid therapy * Those with severe systemic disease (e.g. advanced renal failure, malignancy)

Treatments Being Tested

DIAGNOSTIC_TEST

Del 1

During cataract surgery, approximately 0.1-0.2 mL of aqueous humor will be sampled with a sterile 27 gauge syringe before viscoelastic is introduced into the anterior chamber. DEL 1 will be analyzed by ELISA

DIAGNOSTIC_TEST

IL 17

During cataract surgery, approximately 0.1-0.2 mL of aqueous humor will be sampled with a sterile 27 gauge syringe before viscoelastic is introduced into the anterior chamber. IL 17 levels will be analyzed by ELISA

Locations (1)

Uşak Training and Research Hospital
Uşak, Uşak, Turkey (Türkiye)