RECRUITINGOBSERVATIONAL
Glofitamab in Real Life
About This Trial
To date, more than 300 patients have been treated with Glofitamab in the Expanded Access Programme (EAP) in France. In this study, it is proposed to perform a retrospective analysis of some of these patients. The aim is to describe the efficacy and safety of Glofitamab in the largest reported real-world cohort, with an expected median follow-up of more than 9 months. Particular focus will be given to the relapsed or refractory chimeric antigen receptors-T (CAR-T) population to confirm the response rates (CRR: 35-39%) of Glofitamab in this population and to assess the optimal timing of therapy initiation \[8, 15\].
Who May Be Eligible (Plain English)
Who May Qualify:
- patient enrolled in the French Glofitamab EAP for R/R DLBCL before 2024 November 1st, 2024
- patient who received at least Obinutuzumab pretreatment and one infusion of Glofitamab
- adult patient
- patient who is informed of the study and who did not oppose to their data collection
Who Should NOT Join This Trial:
- none
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* patient enrolled in the French Glofitamab EAP for R/R DLBCL before 2024 November 1st, 2024
* patient who received at least Obinutuzumab pretreatment and one infusion of Glofitamab
* adult patient
* patient who is informed of the study and who did not oppose to their data collection
Exclusion Criteria:
* none
Treatments Being Tested
DRUG
Glofitamab
Glofitamab received for DLBCL in Early Phase Access
Locations (20)
CH Victor Dupouy
Argenteuil, France
CH d'Avignon - Hôpital Henri Dufaut
Avignon, France
CH de la Côte Basque
Bayonne, France
CHRU Besançon - Hôpital Minjoz
Besançon, France
Hopital D'Instruction Des Armees Percy
Clamart, France
Hopital Henri Mondor
Créteil, France
CHU de Dijon - Hôpital le Bocage
Dijon, France
CH de Dunkerque
Dunkirk, France
CHU de Grenoble - Hôpital Albert Michallon
La Tronche, France
Hôpital de Libourne
Libourne, France
CHRU de LILLE - Claude Huriez
Lille, France
Hopital Saint Vincent-de-Paul
Lille, France
Centre Léon Bérard
Lyon, France
INSTITUT PAOLI CALMETTES - Service Hématologie
Marseille, France
Clinique du Pont de Chaume
Montauban, France
CH de Mulhouse Sud Alsace
Mulhouse, France
CHR d'Orléans
Orléans, France
Hopital Saint-Louis
Paris, France
Chu de Bordeaux - Hopital Haut-Leveque
Pessac, France
CHU Lyon Sud
Pierre-Bénite, France