First-in-human Safety and Immunogenicity Study of SCB-1022 and SCB-1033 in Healthy Older Adults

Who May Qualify: - Male and female participants 60 to 85 years of age at the screening visit. - Individuals willing and able to comply with study requirements, including all scheduled visits, vaccination, laboratory tests, and other study procedures. - Individuals willing and able to give an willing to sign a consent form, prior to screening. - Healthy participants as determined by medical history, physical examination, and clinical judgment of the investigator; participants with pre-existing stable medical conditions can be included. Please refer to Protocol for full list of Inclusion and Exclusion criteria. Who Should NOT Join This Trial: - Pregnancy or potential to become pregnant during the study. - Acute disease or fever (≥38°C) at time of vaccination. - History of Guillain-Barré Syndrome (GBS). - Recurrent or un-controlled neurological disorders or seizures. - Serious or unstable chronic illnesses. Please refer to Protocol for full list of Inclusion and Exclusion criteria. Always talk to your doctor about whether this trial is right for you.