RECRUITINGINTERVENTIONAL
CTFFR and Prediction of Non-Significant CAD Lesions
Evaluation of the Ability of CTFFR to Determine Non-significant Lesions of Coronary Disease Based on MACE in One-year Follow-up of Patients (Seeing Beyond the Stenosis: CTFFR and MACE in a One-Year Follow-Up)
About This Trial
In this prospective cohort study, 250 patients with suspected or known CAD and at least one intermediate coronary lesion (50-70% stenosis) who had a NiFFR value greater than 0.80 underwent coronary computed tomography angiography (CCTA) with NiFFR assessment. Patients were followed for one year to monitor for MACE
Who May Be Eligible (Plain English)
Who May Qualify:
- Patients were enrolled if they had at least one intermediate coronary lesion (classified as 50-70% diameter stenosis on visual judgment) on CCTA and then underwent FFR testing
Who Should NOT Join This Trial:
- Patients having past coronary artery bypass graft surgery (CABG)
- previous PCI in the target vascular
- significant renal impairment define with eGFR \< 30 mL/min/1.73 m²
- contrast allergy
- poor image quality that prevented appropriate CCTA or CT-FFR analysis
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Patients were enrolled if they had at least one intermediate coronary lesion (classified as 50-70% diameter stenosis on visual judgment) on CCTA and then underwent FFR testing
Exclusion Criteria:
* Patients having past coronary artery bypass graft surgery (CABG)
* previous PCI in the target vascular
* significant renal impairment define with eGFR \< 30 mL/min/1.73 m²
* contrast allergy
* poor image quality that prevented appropriate CCTA or CT-FFR analysis
Treatments Being Tested
DIAGNOSTIC_TEST
NIFFR
Fractional flow reserve derived from CT angiography from lesion between 50-70%
Locations (1)
Professor Kojuri Cardiology Clinic
Shiraz, Fars, Iran