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RECRUITINGINTERVENTIONAL

oCular Examination at Cell RESolution With Optical TransmissionTomography

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Understanding the pathogenesis of eye diseases has benefited greatly from recent advances in ophthalmic imaging. However, current clinical imaging systems, such as optical coherence tomography (OCT), are limited in terms of resolution, acquisition speed or access to certain eye functions. Our team has participated in the development of a new generation of imaging technology known as optical transmission tomography (OTT), which enables imaging of the anterior parts of the eye with high cellular resolution, a wide field of view and reduced examination delay.

Who May Be Eligible (Plain English)

Who May Qualify: For Patients: - 200 subjects aged 18 to 80 years; - Male or female; - with an ocular disease affecting the cornea, ocular surface, lens (cataract) or glaucoma, or requiring refractive surgery or post-refractive surgery follow-up; - Are covered by the French Assurance Maladie; - Have signed an express, free and willing to sign a consent form form. For Healthy volunteers: - 100 subjects aged 18 to 80 years; - Male or female; - Healthy subjects with no known pathology directly or indirectly affecting ocular structures; - Covered by the French Assurance Maladie. - Having signed an express, free and willing to sign a consent form form. Who Should NOT Join This Trial: For all participants: - Inability to hold a still position on a standard ophthalmic chin rest; - Conjunctivitis or other contagious contact disease in active phase; - Having an implanted pacemaker or other electronic medical device; - Having a predisposition to iridocorneal angle closure; - Vulnerable persons or persons under legal protection (pregnant or breast-feeding women; persons under guardianship, Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: For Patients: * 200 subjects aged 18 to 80 years; * Male or female; * with an ocular disease affecting the cornea, ocular surface, lens (cataract) or glaucoma, or requiring refractive surgery or post-refractive surgery follow-up; * Are covered by the French Assurance Maladie; * Have signed an express, free and informed consent form. For Healthy volunteers: * 100 subjects aged 18 to 80 years; * Male or female; * Healthy subjects with no known pathology directly or indirectly affecting ocular structures; * Covered by the French Assurance Maladie. * Having signed an express, free and informed consent form. Exclusion Criteria: For all participants: * Inability to hold a still position on a standard ophthalmic chin rest; * Conjunctivitis or other contagious contact disease in active phase; * Having an implanted pacemaker or other electronic medical device; * Having a predisposition to iridocorneal angle closure; * Vulnerable persons or persons under legal protection (pregnant or breast-feeding women; persons under guardianship,

Treatments Being Tested

DEVICE

Optical Transmission Tomography (OTT)

Multiple imaging sessions added by research using the systems described (OTT) will be carried out by two different operators at different positions during these sessions.

DEVICE

Optical Coherence Tomography (OCT)

Multiple imaging sessions (OCT) already used in standard of care will be performed by two different operators at different positions during these sessions.

DEVICE

Specular Microscopy (SM)

Multiple imaging sessions (SM) already used in standard of care will be performed by two different operators at different positions during these sessions.

Locations (1)

Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Paris, France