RECRUITINGINTERVENTIONAL
Test of Target Engagement of Ambiguity Aversion
Computational Modeling of Ambiguity Aversion in Internalizing Disorders: Neural and Behavioral Markers, and a Test of Target Engagement
About This Trial
The present work aims to test whether a single session intervention alters ambiguity aversion, both in terms of people's decision making and their brain responses to ambiguous choices.
Who May Be Eligible (Plain English)
Who May Qualify:
1. Ages 25 to 60
2. Right-handed
3. Ability to read and write English
4. Capacity to provide willing to sign a consent form
5. Intolerance of uncertainty score ≥ -0.5 standard deviation below the mean (31st percentile)
Who Should NOT Join This Trial:
1. Personal history of psychosis, mania, or hypomania
2. Personal history of autism spectrum disorder
3. IQ \< 80 as determined by the Wechsler Test of Adult Reading
4. Head injury with greater than 120 seconds loss of consciousness
5. Neurological condition (e.g., epilepsy, Parkinson's, cerebral palsy, history of stroke)
6. Currently pregnant
7. Use of any implanted electrical device (e.g., pacemaker, spinal stimulator, vagal nerve stimulator, Inspire sleep apnea device, etc.).
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
1. Ages 25 to 60
2. Right-handed
3. Ability to read and write English
4. Capacity to provide informed consent
5. Intolerance of uncertainty score ≥ -0.5 standard deviation below the mean (31st percentile)
Exclusion Criteria:
1. Personal history of psychosis, mania, or hypomania
2. Personal history of autism spectrum disorder
3. IQ \< 80 as determined by the Wechsler Test of Adult Reading
4. Head injury with greater than 120 seconds loss of consciousness
5. Neurological condition (e.g., epilepsy, Parkinson's, cerebral palsy, history of stroke)
6. Currently pregnant
7. Use of any implanted electrical device (e.g., pacemaker, spinal stimulator, vagal nerve stimulator, Inspire sleep apnea device, etc.).
Treatments Being Tested
BEHAVIORAL
Uncertainty-focused single session intervention
Digitally/computer administered 30-minute self-guided intervention for adults ages 25-60
BEHAVIORAL
Maintaining a healthy lifestyle single session intervention
Digitally/computer administered 30-minute self-guided intervention for adults ages 25-60
Locations (1)
Northwestern University
Chicago, Illinois, United States