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RECRUITINGPhase 3INTERVENTIONAL

Randomized Withdrawal Study in Patients With Schizophrenia

A Multicenter, Double-Blind, Randomized Withdrawal Study in Patients With Schizophrenia Receiving Either Iloperidone Long-Acting Injection (LAI) or Placebo Injection

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The purpose of this research is to evaluate the efficacy of dosing iloperidone long-acting injection (LAI) compared to placebo in preventing the exacerbation of symptoms in patients with schizophrenia.

Who May Be Eligible (Plain English)

Who May Qualify: - Males or females 18 to 65 years of age (inclusive) - Diagnosed with schizophrenia per DSM-5 criteria - In need of ongoing psychiatric treatment Who Should NOT Join This Trial: - DSM-5 diagnosis of a psychiatric disorder other than schizophrenia that was the primary focus of treatment within the previous six months Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Males or females 18 to 65 years of age (inclusive) * Diagnosed with schizophrenia per DSM-5 criteria * In need of ongoing psychiatric treatment Exclusion Criteria: * DSM-5 diagnosis of a psychiatric disorder other than schizophrenia that was the primary focus of treatment within the previous six months

Treatments Being Tested

DRUG

iloperidone

iloperidone LAI

DRUG

placebo

matching placebo

Locations (20)

Vanda Investigational Site
Rogers, Arkansas, United States
Vanda Investigational Site
Costa Mesa, California, United States
Vanda Investigational Site
Lemon Grove, California, United States
Vanda Investigational Site
Oceanside, California, United States
Vanda Investigational Site
Pico Rivera, California, United States
Vanda Investigational Site
San Diego, California, United States
Vanda Investigational Site
Walnut Creek, California, United States
Vanda Investigational Site
North Miami, Florida, United States
Vanda Investigational Site
Atlanta, Georgia, United States
Vanda Investigational Site
Peachtree Corners, Georgia, United States
Vanda Investigational Site
Chicago, Illinois, United States
Vanda Investigational Site
Flowood, Mississippi, United States
Vanda Investigational Site
Saint Charles, Missouri, United States
Vanda Investigational Site
St Louis, Missouri, United States
Vanda Investigational Site
Las Vegas, Nevada, United States
Vanda Investigational Site
Marlton, New Jersey, United States
Vanda Investigational Site
Staten Island, New York, United States
Vanda Investigational Site
Austin, Texas, United States
Vanda Investigational Site
Houston, Texas, United States
Vanda Investigational Site
Irving, Texas, United States