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RECRUITINGOBSERVATIONAL

Identification of Specific Molecular Signatures in Pediatric, Adolescent, and Young Adult Rhabdomyosarcoma Through Spatial Proteome Analysis Using Mass Spectrometry

Identification de Signatures moléculaires spécifiques Dans le Rhabdomyosarcome de l'Enfant, de l'Adolescent et du Jeune Adulte, Par Analyse Spatiale du protéome Par spectrométrie de Masse

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This non-interventional study aims to develop spatial proteomics for analyzing small FFPE tumor samples in rhabdomyosarcoma. It will identify molecular signatures linked to tumor regions, subtypes, survival, and treatment resistance, using pre-existing samples and data.

Who May Be Eligible (Plain English)

Who May Qualify: - Age between 0 and 25 years at the time of initial diagnosis - Diagnosis of rhabdomyosarcoma confirmed histologically - Care at the Oscar Lambret Center between January 2005 and November 2024 - No objection to the re-use of data and biological samples collected as part of care for research activities. Who Should NOT Join This Trial: - Unavailability of biological sample in FFPE from biopsy and/or surgical specimen for diagnosis at Centre Oscar Lambret; - Patient under guardianship or trusteeship. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Age between 0 and 25 years at the time of initial diagnosis * Diagnosis of rhabdomyosarcoma confirmed histologically * Care at the Oscar Lambret Center between January 2005 and November 2024 * No objection to the re-use of data and biological samples collected as part of care for research activities. Exclusion Criteria: * Unavailability of biological sample in FFPE from biopsy and/or surgical specimen for diagnosis at Centre Oscar Lambret; * Patient under guardianship or trusteeship.

Treatments Being Tested

OTHER

None AHT

This study does not involve any interventions. It analyzes pre-existing biological samples (FFPE tumor tissue) and clinical data from patients with rhabdomyosarcoma.

Locations (1)

Oscar Lambret Center
Lille, Nord, France