Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Who May Qualify: - Signed willing to sign a consent form must be obtained prior to participation in the study. - Males or females ≥ 18 years of age - Within 14 days of a successful percutaneous coronary intervention (PCI) or peripheral endovascular intervention (PVI) for symptomatic CAD or lower extremity PAD - Patients undergoing planned staged interventions are eligible for randomization only after the last planned intervention Who Should NOT Join This Trial: - Planned future PCI or PVI - Current or planned use of an open-label PCSK9 inhibitor during the study - Any prior treatment with inclisiran - Active or planned participation in another clinical study involving investigational drugs or devices during the study - Any serious liver disease, metabolic disease, neoplasm, end-stage kidney disease, or other condition in the opinion of the investigator that would inhibit trial participation or confound trial results - Any other reason why, in the opinion of the investigator, the participant would not be suitable for study participation including safety considerations and the ability to adhere to protocol activities - Patients taking prohibited therapies as listed in Section 6.6.3 - Pregnant or breast-feeding women Always talk to your doctor about whether this trial is right for you.