RECRUITINGINTERVENTIONAL
Study of the Impact of Time of Vaccination on Response to Influenza Vaccine in Patients With Chronic Renal Failure
Study of the Impact of Time of Vaccination on Response to Influenza Vaccine in Patients With Chronic Renal Failure - CHRONOVAX 2
About This Trial
Immune response to influenza vaccine in patients with chronic renal insufficiency.
Who May Be Eligible (Plain English)
Who May Qualify:
- Chronic renal failure patient at stage 4 or 5 (i.e. estimated GFR \< 30mL/min/1.73m2); or Dialysis patient; or renal transplant patient regardless of GFR;
- Age ≥ 18 years;
- Indication for influenza vaccination;
- Express free and willing to sign a consent form.
Who Should NOT Join This Trial:
- Known hypersensitivity to influenza vaccine or egg proteins;
- Previous influenza vaccination for the current season;
- Current infection;
- Current acute illness;
- Treatments with a major impact on vaccine response:
- Treatment of rejection within the previous 3 months;
- Renal transplantation with induction performed within the previous 6 months;
- Immunosuppressive treatment including CTLA4 agonist, complement inhibitor, anti-CD20;
- Treatments that may distort the serological response: Polyvalent immunoglobulin infusion within the preceding 3 months;
- Vulnerable persons (minors, adults under guardianship or trusteeship, persons deprived of their liberty, persons unable to speak French);
- Subjects not affiliated to Social Security.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Chronic renal failure patient at stage 4 or 5 (i.e. estimated GFR \< 30mL/min/1.73m2); or Dialysis patient; or renal transplant patient regardless of GFR;
* Age ≥ 18 years;
* Indication for influenza vaccination;
* Express free and informed consent.
Exclusion Criteria:
* Known hypersensitivity to influenza vaccine or egg proteins;
* Previous influenza vaccination for the current season;
* Current infection;
* Current acute illness;
* Treatments with a major impact on vaccine response:
* Treatment of rejection within the previous 3 months;
* Renal transplantation with induction performed within the previous 6 months;
* Immunosuppressive treatment including CTLA4 agonist, complement inhibitor, anti-CD20;
* Treatments that may distort the serological response: Polyvalent immunoglobulin infusion within the preceding 3 months;
* Vulnerable persons (minors, adults under guardianship or trusteeship, persons deprived of their liberty, persons unable to speak French);
* Subjects not affiliated to Social Security.
Treatments Being Tested
OTHER
Vaccine injection
Injection of the vaccine in chronic renal insufficiency patients.
Locations (1)
CHU Nice - Hôpital Pasteur 2
Nice, Alpes-Maritimes, France