RECRUITINGINTERVENTIONAL

Intensive Combination Approach to Rollback the HIV Epidemic in Nigerian Youth (iCARE) Plus Effectiveness/Implementation Hybrid Study

Intensive Combination Approach to Rollback the HIV Epidemic in Nigerian Youth (iCARE) Plus Effectiveness/Implementation Hybrid Study: Aim 2

About This Trial

Two combination interventions (HIV Case Finding Intervention and HIV Treatment Intervention), each with mHealth and Peer Navigation components, will be evaluated in two 48-week parallel hybrid effectiveness/implementation trials among youth aged 15-24 in Nigeria.

Who May Be Eligible (Plain English)

Who May Qualify: HIV Case Finding Intervention: - Aged 15 to 24 - Male birth sex of any current gender identity - Understand basic English, Yoruba, Hausa, Igbo or Pidgin English For the PrEP component, must also be HIV-negative HIV Treatment Intervention: - Aged 15 to 24 - HIV seropositive - Initiating ART for the first time at a Clinical Research Performance Site (CRPS) clinic or satellite clinic - Understand basic English, Yoruba, Hausa, Igbo or Pidgin English - Intention to remain a CRPS patient during follow-up Who Should NOT Join This Trial: - Unable to provide consent - No parental permission if aged 15 and not emancipated Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Inclusion Criteria: HIV Case Finding Intervention: * Aged 15 to 24 * Male birth sex of any current gender identity * Understand basic English, Yoruba, Hausa, Igbo or Pidgin English For the PrEP component, must also be HIV-negative HIV Treatment Intervention: * Aged 15 to 24 * HIV seropositive * Initiating ART for the first time at a Clinical Research Performance Site (CRPS) clinic or satellite clinic * Understand basic English, Yoruba, Hausa, Igbo or Pidgin English * Intention to remain a CRPS patient during follow-up Exclusion Criteria: * Unable to provide consent * No parental permission if aged 15 and not emancipated

Treatments Being Tested

BEHAVIORAL

Testing Peer navigation

Peer navigators will promote HIV testing in YMSM and linkage to care if HIV-positive

BEHAVIORAL

PrEP Intervention

Motivational-interviewing to promote uptake of PrEP among those who test HIV-negative

BEHAVIORAL

Treatment Peer Navigation

Peer navigators will provide assistance and support to youth with HIV to optimize adherence to ART

BEHAVIORAL

Social Media Outreach

Social media outreach to identify youth at risk for HIV

BEHAVIORAL

SMS Test messaging

Text (SMS) messages to remind and encourage youth to adhere to their ART

OTHER

Adherence standard of care

Standard of care HIV treatment adherence

Locations (6)

University of Uyo Teaching Hospital

Uyo, Akwa Ibom State, Nigeria

Federal Medical Center

Makurdi, Benue State, Nigeria

University of Nigeria Teaching Hospital

Enugu, Enugu State, Nigeria

Aminu Kano Teaching Hospital

Kano, Kano State, Nigeria

Lagos University Teaching Hospital

Lagos, Lagos, Nigeria

Taraba State Specialist Hospital

Jalingo, Taraba State, Nigeria