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RECRUITINGOBSERVATIONAL

Brain and Behavior Influences on Obesity Development From Infancy Through Childhood

Early Brain Development and Child Nutrition and Obesity

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The investigators project, RESONATE, aims to investigate why some children develop obesity. To do this it uses data on eating and eating-related behaviors, genetic and environmental factors, and brain structure and function. This data is collected in a sub-sample of RESONANCE, a large study of families of children from infancy through childhood. The results will lay foundations for the development of early interventions to prevent or treat obesity.

Who May Be Eligible (Plain English)

Who May Qualify: - Participants from the RESONANCE cohort are eligible if the participant will reach 7-12 years of age during the proposed project period and have no food allergies. Who Should NOT Join This Trial: - Exclusion criteria for RESONANCE include: 1. In utero exposure to alcohol, cigarette, or illicit substances; 2. First trimester fetal US abnormalities; 3. Complicated pregnancy (e.g., pre-eclampsia); 4. Complicated delivery, including APGAR scores less than 8 and/or neonatal intensive care unit (NICU) admission; 5. History of neurological (e.g., epilepsy), psychiatric (e.g., anxiety or depression requiring treatment with medication) or developmental disorder (e.g., autism spectrum disorder (ASD), dyslexia); 6. Contraindications for MRI including metal in the body, claustrophobia. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Participants from the RESONANCE cohort are eligible if the participant will reach 7-12 years of age during the proposed project period and have no food allergies. Exclusion Criteria: * Exclusion criteria for RESONANCE include: 1. In utero exposure to alcohol, cigarette, or illicit substances; 2. First trimester fetal US abnormalities; 3. Complicated pregnancy (e.g., pre-eclampsia); 4. Complicated delivery, including APGAR scores less than 8 and/or neonatal intensive care unit (NICU) admission; 5. History of neurological (e.g., epilepsy), psychiatric (e.g., anxiety or depression requiring treatment with medication) or developmental disorder (e.g., autism spectrum disorder (ASD), dyslexia); 6. Contraindications for MRI including metal in the body, claustrophobia.

Locations (4)

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Baltimore, Maryland, United States
Johns Hopkins University School of Medicine
Baltimore, Maryland, United States
Rhode Island Hospital
Providence, Rhode Island, United States
University of Washington
Seattle, Washington, United States