RECRUITINGOBSERVATIONAL
Role of Corneal Nerves in Dry Eye Disease
Association Between Corneal Sensitivity, Nerve Morphology, Tear Film Homeostasis and Dry Eye Symptoms
About This Trial
This study aims to determine whether corneal nerve function and morphology are affected by tear film instability and ocular surface homeostasis loss. Additionally, it seeks to investigate whether these factors vary based on the severity of dry eye symptoms.
Who May Be Eligible (Plain English)
Who May Qualify:
- Group with DED: Diagnosis of DED based on the TFOS DEWS II report
- Group without DED: No diagnosis of DED
Who Should NOT Join This Trial:
- Who Should NOT Join This Trial:
- Systemic disease that may affect ocular health and innervation
- injury or history of operations on the anterior or posterior segment of the eye, which can affect the corneal structure and physiology
- regular application of systemic or ocular medication known to affect the tear film except from DED medications
- eye drops or makeup on the day of measurement.
Remarks:
Contact lens wearers are asked not to wear contact lenses for 1 week before the first appointment.
Participant with DED medications will be asked to use only conservative-free eye drops on the days of examination
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Group with DED: Diagnosis of DED based on the TFOS DEWS II report
* Group without DED: No diagnosis of DED
Exclusion Criteria:
* Exclusion criteria:
* Systemic disease that may affect ocular health and innervation
* injury or history of operations on the anterior or posterior segment of the eye, which can affect the corneal structure and physiology
* regular application of systemic or ocular medication known to affect the tear film except from DED medications
* eye drops or makeup on the day of measurement.
Remarks:
Contact lens wearers are asked not to wear contact lenses for 1 week before the first appointment.
Participant with DED medications will be asked to use only conservative-free eye drops on the days of examination
Locations (1)
Institute of Optometrym FHNW
Olten, Switzerland